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Research could help search for birth defect vaccine

Posted: 20 Oct 2015

Researchers at Tulane National Primate Research Center (TNPRC) and Duke University have developed a new model that could bring science one step closer to developing a vaccine against congenital cytomegalovirus (CMV), one of the world's leading infectious causes of birth defects. 

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Experimental Aerosol TB Vaccine Protects Monkeys, NIH-Funded Researchers Find

Posted: 16 Oct 2015

Researchers funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have developed an investigational aerosol tuberculosis (TB) vaccine that induced potent immune responses in a small number of rhesus macaques and protected them against pulmonary infection with Mycobacterium tuberculosis(Mtb). The findings appear in Nature Communications.

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Tulane Researchers Working on New Tuberculosis Vaccine

Posted: 15 Oct 2015

Researchers at the Tulane National Primate Research Center (TNPRC) are leading efforts to find a new vaccine for tuberculosis, one of the world's deadliest diseases. Tuberculosis, a contagious infection of the lungs, affected more than nine million people in 2013, killing more than one million.

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The Search for Persisters

Posted: 24 Sep 2015

It starts with a tick bite. This may be followed by the characteristic bullseye rash. And then the other symptoms of Lyme disease appear. Fever, fatigue, body aches, and headaches can all set in.

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Animal research crucial to creating AIDS treatments

Posted: 24 Jul 2015

Scientists in Philadelphia may be on the cusp of curing AIDS.

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Animal Testing and Its Gifts To Humans

Posted: 22 May 2015

Patients with aggressive brain tumors finally have reason for hope. Thanks to the work of scientists and physicians at Duke University, an experimental new treatment for glioblastoma multiforme, or GBM—an aggressive tumor that kills about 12,000 people in the U.S. each year—is saving the lives of patients who, just months ago, had little hope of survival.

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Bay Area Lyme Foundation's LymeAid® Brings Celebrities and Scientists Together To Help Accelerate Medical Breakthroughs for Lyme Disease

Posted: 22 May 2015

PORTOLA VALLEY, Calif., May 19, 2015 /PRNewswire/ -- On Sunday, May 17, Bay Area Lyme Foundation, the leading national nonprofit funder of innovative Lyme disease research, hosted more than 400 celebrities, philanthropists and noteworthy scientists at the third annual LymeAid®. The benefit dinner and concert raised approximately $600,000, of which 100% will go directly to fund research for Lyme disease. More than 300,000 Americans are diagnosed with this potentially debilitating disease each year.

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Increasing evidence points to inflammation as source of nervous system manifestations of Lyme disease

Posted: 16 Apr 2015

Philadelphia, PA, April 16, 2015 – About 15% of patients with Lyme disease develop peripheral and central nervous system involvement, often accompanied by debilitating and painful symptoms. New research indicates that inflammation plays a causal role in the array of neurologic changes associated with Lyme disease, according to a study published in The American Journal of Pathology. The investigators at the Tulane National Primate Research Center and Louisiana State University Health Sciences Center also showed that the anti-inflammatory drug dexamethasone prevents many of these reactions.

"These results suggest that inflammation has a causal role in the pathogenesis of acute Lyme neuroborreliosis," explained Mario T. Philipp, PhD, Professor of Microbiology and Immunology and chair of the Division of Bacteriology and Parasitology at Tulane National Primate Research Center (Covington, LA).

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Could experimental ricin vaccine protect people?

Posted: 17 Mar 2015

If an experimental ricin vaccine can protect non-human primates, would it also work to protect people from the deadly toxin? 

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