Smriti Mehra, Ph.D.
M.Sc., Biochemistry, University of Delhi, Delhi, India
Ph.D., Genetics, University of Delhi, Delhi, India
As an Assistant Professor-Research within the Division of Pathobiological Sciences at the LSU School of Veterinary Medicine, I am responsible for developing my independent tuberculosis research program. The LSU position is my primary appointment. Additionally I continue to hold the position of Research Assistant Professor at the Division of Microbiology, Tulane National Primate Research Center, via a memorandum of understanding. I employ a nonhuman primate model of TB, which is based on infecting rhesus macaques with infectious aerosols of Mycobacterium tuberculosis (Mtb). My research focus is to:
i) Evaluate potential novel vaccines for their safety and efficacy. These candidates could be attenuated whole-bacterium, subunit, DNA-based or viral vector based;
ii) Study the role of host negative regulators of T cell function e.g. IDO in modulating immune responses to Mtb infection in macaques;
iii) To test the safety and efficacy of recombinant/attenuated BCG strains as part of prime-boost vaccines against Mtb infection, again using the macaque model of TB.
The TNPRC is a division of Tulane University (985) 871-6201 firstname.lastname@example.org