Ph.D., 2000, Tulane University
Phone: (504) 862-3301
3050 Percival Stern Hall
The broad goal of Dr. Daniel’s research is to understand mechanisms by which estrogens and androgens impact areas of the brain important for cognition. Current work in the lab is focused on the impact of these hormones on the brain and cognition across the lifespan, from early in development during which they help organize mammalian brains as male or female to later in life during which changes in their levels impact the aging brain. Research is conducted in rodent models and experimental approaches used in the lab include behavioral analyses as well as biochemical and molecular assays.
Daniel, J.M. (2013). Estrogens, estrogen receptors and female cognitive aging: Impact of timing. Invited review. Hormones and Behavior, 63: 231-237.
Witty, C.F., Gardella, L.P., Perez, M.C., Daniel, J.M. (2013). Short-term estradiol administration in aging ovariectomized rats provides lasting benefits for memory and the hippocampus: a role for insulin-like growth factor-I. Endocrinology,154: 842-852.
Witty, C.F., Foster, T.C., Semple-Rowland, S.L., Daniel, J.M. (2012). Increasing hippocampal estrogen receptor alpha levels via viral vectors increases MAP kinase activation and enhances memory in aging rats in the absence of ovarian estrogens. PLOS ONE, 7(12):e51385.
Nelson, B.S., Witty, C.F., Williamson, E.A., Daniel, J.M. (2012). A role for actin rearrangement in object placement memory in female rats. Neurobiology of Learning and Memory, 98: 284-90.
Bayless, D.W., Darling, J.S., Stout, W.J., Daniel, J.M. (2012). Sex differences in attentional processes in adult rats as measured by performance on the 5-choice serial reaction time task. Behavioural Brain Research, 235, 48-54.
Stelly, C.E., Cronin, J., Daniel, J.M, Schrader L.A. (2012). Long‐term oestradiol treatment enhances hippocampal synaptic plasticity that is dependent on muscarinic acetylcholine receptors in ovariectomised female rats. Journal of Neuroendocrinology, 24, 887-896.
Winsauer, P.J., Daniel, J.M., Filipeanu, C.M., Leonard, S.T., Hulst, J.L., Rodgers, S.P., Lassen-Greene, C.L., Sutton, J.L. (2011) Long-term behavioral and pharmacodynamic effects of delta-9-tetrahydrocannabinol in female rats depend on ovarian hormone status. Addiction Biology, 16: 64-81.
Daniel, J.M. and Bohacek, J. (2010). The critical period hypothesis of estrogen effects on cognition: Insights from basic research. Invited review for publication in a special issue, Estrogen Action in the Brain, of Biochimica et Biophysica Acta – General Subjects, 1800: 1068-1076.
Rodgers, S.P., Bohacek, J. & Daniel, J.M. (2010). Transient estradiol exposure during middle-age in ovariectomized rats exerts lasting effects on cognitive function and the hippocampus. Endocrinology,151:1194-203.
Bohacek, J. & Daniel, J.M. (2010). The beneficial effects of estradiol on attentional processes are dependent on timing of treatment initiation following ovariectomy in middle-aged rats. Psychoneuroendocrinology 35:694-705.
Bohacek, J. & Daniel, J.M. (2009). Ability of oestradiol administration to regulate protein levels of oestrogen receptor alpha in the hippocampus and prefrontal cortex of middle-aged rats is altered following long-term ovarian hormone deprivation. Journal of Neuroendocrinology 21, 640–647.
Bohacek, J., Bearl A.M. & Daniel, J.M. (2008). Long-term ovarian hormone deprivation alters the ability of subsequent oestradiol replacement to regulate choline acetyltransferase protein levels in the hippocampus and prefrontal cortex of middle-aged rats. Journal of Neuroendocrinology, 20, 1023-1027.
Department of Psychology • 2007 Percival Stern Hall • New Orleans, LA 70118 • Phone: 504-865-5331 • email@example.com