University of Glasgow, Wellcome Surgical Institute, Neuroscience, 1992
Associate Professor of Cell and Molecular Biology
Dr. Inglis studies mechanisms of neuronal plasticity during development, and how this might relate to plasticity in later life. She uses both molecular biology and in vivo neurochemical techniques. This work is important in understanding and treating neurodegenerative disease. Dr. Inglis teaches NSCI 435/635 (Developmental Neurobiology) and NSCI 437/637 (Molecular Neurobiology).
Developmental neurobiology; neuronal plasticity. Studies include molecular interactions that underlie neuronal plasticity during development. Viral vectors and transient transfection techniques are used in tissue culture and in vivo systems. In addition, integrated neuronal function is studied using in vivo microdialysis to measure changes in neurotransmitter release.
Inglis, F.M., Crockett, R., Korada, S., Abraham, W.C., Hollmann, M., Kalb, R.G., 2002. The AMPA receptor subunit GluR1 regulates dendritic architecture of motor neurons. J. Neurosci. 22:8042-51.
Inglis, F.M., Crockett, R., Korada, S., Neve, R.L., Hollman, M., Kalb, R.G. (2000) Expression of GluR1 AMPA receptor subunits modifies dendritic architecture in developing motor neurons(submitted).
Wang T., Inglis, F.M., Kalb, R.G. (2000) Defective fluid and HCO3 absorption in the proximal tubule of nitric oxide synthase knockout mice. American Journal of Physiology 279:F518-F524.
Inglis, F.M., Zuckerman, K.E., Kalb, R.G. (2000) Experience-dependent development of motor neurons. Neuron 26:299-305.
McLaughlin, M., Inglis, F.M., Ross, B.M., Breen, K.C., McCulloch, J. (1999) Modest cholinergic deafferentation fails to alter hippocampal G-proteins. Neurochem. Intl. 35:59-64.
Morrow, B.A., Elsworth, J.E., Inglis, F.M., Roth, R.H. (1999) An antisense oligonucleotide reverses the footshock-induced expression of Fos in the rat medial prefrontal cortex and the subsequent expression of conditioned fear-induced immobility. J. Neuroscience 19:5666-5673.
Youngren, K.D., Inglis, F.M., Pivirotto, P.J., Jedema, H.P., Bradberry, C.W., Goldman-Rakic, P.S., Roth, R.H., Moghaddam, B. (1999) Clozapine preferentially increases dopamine release in the rhesus monkey prefrontal cortex compared with the caudate nucleus. Neuropsychopharmacology 20:403-412.
Inglis, F.M., Moghaddam, B. (1999) Dopaminergic innervation of the amygdala is highly responsive to stress. J. Neurochem. 72:1088-1094.
Dictionary of Biological Psychology, Philip Winn, Ed. Routledge, U.K. (60 definitions written, 100-800 words each; subjects covered include molecular and cell biology, genetics, and cerebral blood flow and brain mapping techniques) (in press).
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