Benjamin Hall, Ph.D.

PhD Simon Fraser University, 2002
BS McGill University
Assistant Professor of Cell and Molecular Biology


Dr. Hall studies the cellular and molecular mechanisms that regulate synapse development and function in the neocortex. Studies in his lab are carried out both in in vitro, cortical networks and in acute brain slices using a combination of techniques in mouse genetics, electrophysiology, molecular biology, and cellular imaging. 

Research Interests

Neocortical development involves the precise elaboration of a network containing billions of neurons and requires the proper initiation, stabilization and maturation of trillions of synaptic contacts. Understanding the cellular mechanisms that regulate cortical synapse development is crucial for a complete understanding of cortical function and thus neurodevelopmental disorders such as schizophrenia and autism.

Representative Publications

SynGAP regulates protein synthesis and homeostatic synaptic plasticity in developing cortical networks.Chih-Chieh Wang, Richard G. Held and Benjamin J. Hall. (2013) PLoS ONE 8(12): e83941.

Neurodevelopmental role for VGLUT2 in pyramidal neuron maturation and spatial learning. Hongbo He, Amanda H. Mahnke, Sukhjeevan Doyle, Ni Fan, Ya-Ping Tan, Chih-Chieh Wang, Benjamin J. Hall, Fiona M. Inglis, Chu Chen, and Jeffrey D. Erickson. (2012) Journal of Neuroscience, 32(45):15886-15901.

The calcium-activated transcription factor NeuroD2 regulates the development of hippocampal mossy fiber synapses in vivo. Scott A. Wilke, Benjamin J. Hall, Joseph K. Antonios, Fading Chen, Katie Tiglio, Megan E. Williams and Anirvan Ghosh. (2012) Neural Development, 7:9.

A critical role for NMDA receptors containing the GluN2B subunit in cortical development and function.  Chih-Chieh Wang, Richard Held, Shiao-Chi Chang, Eric Delpire, Anirvan Ghosh and Benjamin J. Hall (2011) Neuron, 72(5): 789-805.

Activity-dependent ubiquitination of GluA1 mediates a distinct AMPA receptor endocytosis and sorting pathway. Lindsay A. Schwarz, Benjamin J. Hall, and Gentry N. Patrick. (2010) J. Neurosci., 30(49): 16718-16729.

Kruppel-like factor 9 is necessary for late-phase neuronal maturation in the developing dentate gyrus and during adult hippocampal neurogenesis.  Kimberly N. Scobie, Benjamin J. Hall, Scott A. Wilke, Kristen C. Klemenhagen, Yoshiaki Fujii-Kuriyama, Anirvan Ghosh, Rene Hen and Amar Sahay. (2009) J. Neurosci., 29(31): 9875-9887.

Regulation of AMPA Receptor Recruitment at Developing Synapses. Benjamin J. Hall and Anirvan Ghosh. (2008) T.I.N.S., 31(2): 82-89.

NR2B Signaling Regulates the Development of Synaptic AMPA Receptor Current. Benjamin J. Hall, Beth Ripley and Anirvan Ghosh. (2007) J. Neurosci., 27(49): 13446-13456.

Regulation of spine morphology and spine density by NMDA receptor signaling in vivo. Sila K Ultanir, Ji-Eun Kim, Benjamin J. Hall, Thomas Deerinck, Mark Ellisman and Anirvan Ghosh. (2007) P.N.A.S., 104(49): 19553-19558.

Regulation of Thalamocortical Patterning and Synaptic Maturation by NeuroD2. Gulayse Ince-Dunn*, Benjamin J. Hall*, Shu-Ching Hu, Beth Ripley, Richard L. Huganir, James M. Olson, Stephen J. Tapscott, and Anirvan Ghosh. (2006) Neuron, 49(5): 683-695.

School of Science and Engineering, 201 Lindy Boggs Center, New Orleans, LA 70118 504-865-5764