"Evolutionary conserved transcriptional response toward BMP signaling in developing mouse and xenopus embryos"
Ken Cho, Ph.D.
Professor and Chair
Department of Developmental and Cell Biology
University of California Irvine
102 Jones Hall
Professor of Practice, Ph.D., University of Bordeaux, France, 2001. Bursting activity
and its synchronization in the hypothalamic magnocellular neurons. Study focuses on
neuronal circuits ending on these neurons that may control their electrical pattern and
therefore their hormonal release. Intracellular patch-clamp recordings in brain slice
preparation and immunocytochemical techniques are used. Dr. Boudaba teaches
CELL 1030, Heredity and Society, CELL 1035, Heredity and Society Laboratory, CELL
2115, General Biology Laboratory, and CELL 4110/6110, Cells and Tissues.
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Associate Professor, Ph.D., Duke University, 1990. Pattern formation during
embryogenesis in the mouse. Cellular and molecular studies using embryonic stem
cell technology are conducted to assess developmental mechanisms in the mouse
embryo. Cell culture, in situ hybridization, and manipulation of gene expression are
used to study the regulatory factors involved in differentiation in the developing
embryo. Dr. Burdsal teaches CELL 375/6750, Cell Biology, CELL 4710/6710, Molecular
Biology of Cancer, CELL 6080, Advanced Developmental and Cell Biology II, and CELL 6840, Current Topics in Developmental Biology. Dr. Burdsal also serves as the Associate Dean for Academic Affairs in the School of Science and Engineering.
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Chair in Cell and Molecular Biology and Professor, Yahoo! Founder Chair in Science and Engineering, Recipient, Provost’s Award for Excellence in Research and Scholarship, 2005. Ph.D. University of Iowa, 1993. Molecular mechanisms and genetic control of vertebrate organogenesis. We are particularly interested in the roles of growth factors and transcription factors in craniofacial and cardiac development and congenital defects. We use a combination of in vivo genetic modifications and in vitro experimental approaches to address fundamental questions in the development of tooth, palate and heart. Dr. Chen teaches CELL 4160/6160, Developmental Biology, CELL 4780/6780, Developmental Genetics.
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Professor of Practice, Ph.D., Tulane University, 1990. Research interests include the
neurophysiology of epilepsy, and developing viral-vector based techniques for gene
transfer to the nervous system.Dr. Cronin teaches CELL 3210/6210, Cellular
Physiology, CELL 6360, Topics in Neurophysiology, and CELL 6660, Topics in
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Professor of Practice, Ph.D., Tulane University, 1998. Coordinator of Cell Biology
Laboratories. Neuroendocrinology; signal transduction in response to cytokines
and growth factors. Dr. Dotson teaches CELL 1030, Heredity and Society,
CELL 2050, Genetics, CELL 3750/6750, Cell Biology, CELL 3755/6755, Cell Biology
Laboratory, and CELL 4110/6110, Cells and Tissues.
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Assistant Professor; Ph.D. Simon Fraser University, 2002. Research interests:
Understanding the cellular and molecular mechanisms that control synapse
development and function in the neocortex. The goal is to understand how
perturbations in synapse maturation and circuit formation relate to behavioral
changes associated with neurodevelopmental disorders. Studies are carried out
both in vitro and in vivo through a combination of techniques in mouse genetics,
electrophysiology, molecular biology, and cellular imaging.
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Professor of Practice; Ph.D., Tulane University, 1992. Research centers around
the understanding of the interaction of the xenobiotics, both naturally occurring and
synthetic, with the cytochrome P450 enzymes and the nuclear steroid hormone
receptor superfamily. My lab uses hormone sensitive cancer cells to study the
mechanism of the effects of these chemicals on P450 isoform induction and
hormone receptor response. We also use a bacterial P450 induction system as a
model for the induction of P450 in mammaliam cells. Purified human P450
isoforms are used to test xenobiotics as inhibitors of certain isoforms that have
been implicated in carcinogenesis. Dr. Hopkins teaches CELL 1035, Heredity and Society Lab, CELL 3035, Molecular Biology Lab, CELL 4010, Cellular Biochemistry, and CELL 4225, Microbiology Lab.
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Associate Professor; Ph.D., University of Glasgow, U.K., 1992. Director, Master's Program in Cell and Molecular Biology. Developmental neurobiology; neuronal plasticity. Studies include molecular interactions that underlie neuronal plasticity during development. Viral vectors and transient transfection techniques are used in tissue culture and in vivo systems. In addition, integrated neuronal function is studied using in vivo microdialysis to measure changes in neurotransmitter release. Dr. Inglis teaches CELL 4350/6350, Developmental Neurobiology, CELL 4370/6370, Molecular Neurobiology, CELL 608, Advanced Developmental and Cell Biology II, and CELL 6840, Current Topics in Developmental Biology.
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Professor, Gerald and Flora Jo Mansfield Piltz Professorship in Cancer Research. Research fields: Molecular biology of breast cancer progression and therapeutic resistance. Signal transduction mediated by the EGFR-family. Regulation of gene expression in schizophrenia. Molecular alterations associated with brain injury. Micro RNA function in development and disease. Mouse models of neural and breast development.
Send e-mail to Dr. Jones. (504) 862-8081
Associate Professor. Research in the Mullin lab is divided between two main Projects. The first project focuses on a new chemical class of antimicrobial agents that we discovered called the DDPs. One of these, 4-DDP1956, is effective in vitro against all gram positive bacterial pathogens tested including methicillin resistant Staphylococcus aureus strains (MRSA), vancomycin resistant enterococci (VRE), and Bacillus anthracis to name a few. We are in the process of identifying the cellular target of 4-DDP1956, and we preparing to begin testing the therapeutic potential of 4-DDP1956 in mice. Finally, we are preparing to synthesize chemical derivatives of 4-DDP1956 that have higher antimicrobial activity and lower toxicity.
Our second major project is to use bacterial fermentation end products to produce liquid fuels for automobiles. We now have several dozen novel bacterial strains that produce liquid fuel that has the same energy content as conventional unleaded gasoline, works in unmodified automobiles, but does not contribute toward increasing the carbon dioxide concentration in the atmosphere. Dr. Mullin teaches CELL 3030/6030, Molecular Biology, and CELL 4220/6220, Microbiology.
John L. & Mary Wright Ebaugh Chair in Science and Engineering and Professor;
Ph.D., University of California Irvine, 1983. Limb development; developmental
growth control; cell-cell interactions; pattern formation. The role of cellular position
and positional information in the control of cell proliferation is being investigated in
the developing mouse limb. We employ embryonic surgical procedures to
investigate spatial and temporal differences in the regulation of cell growth by
introducing cells that have been characterized in vitro. By using a combination of in
vitro and in vivo approaches, our long term goal is to understand how cellular
interactions regulate the reproducible patterns of proliferation during limb development. Dr. Muneoka teaches CELL 4130/6130, Embryology, CELL 6080, Advanced Developmental and Cell Biology II, and CELL 6840, Current Topics in Developmental Biology.
Assistant Professor, PhD., Tulane University, 1997. Molecular mechanisms of
synaptic plasticity and learning and memory. Techniques include: patch clamp
electrophysiology in brain slices, behavioral paradigms, molecular biology and
biochemistry. Our ultimate goal is to better understand how modulation of ion
channels regulates neuronal excitability and synaptic plasticity in the context of
learning and memory. Dr. Schrader teaches CELL 3320, Systems Neuroscience.
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Jeffrey G. Tasker
Recipient, Provost's Award for Excellence in Research and Scholarship, 2005
Catherine and Hunter Pierson Chair in Neuroscience; Ph.D., University of
Bordeaux, France, 1986. Intracellular and patch-clamp electrophysiology using in
vitro brain slices. Study of membrane electrical properties, synaptic circuits and
hormone regulation of hypothalamic neuroendocrine cells. Combined
electrophysiological and neuroanatomical studies with intracellular markers,
histochemical and immunocytochemical techniques. Dr. Tasker teaches CELL 3310/6310, Cellular Neuroscience, CELL 6360, Topics in Neurophysiology, and CELL 6550, Synaptic Organization of the Brain.
Leonard B. Thien
Professor; Ph.D., University of California, 1968. Evolution and molecular
systematics are studied using a combination of PCR, nucleotide sequencing and
morphometric analysis. Other areas of interest include ant-plant interactions,
reproductive biology of primitive angiosperms and ecology of the Mississippi delta
ecosystem. Dr. Thien teaches CELL 1010, General Biology, CELL 3030/6030,
Molecular Biology, and CELL 4440/6440, Advanced Molecular Biology.
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Assistant Professor. Ph.D., Indian Institute of Science, 1999. Research Fields:
Hormonal control of genes and behavior; hormone-mediated signaling in neurons
and glia. Techniques include: cell cultures, behavioral paradigms, molecular
biology and biochemistry. Our aim is to understand how different modes of
hormone signaling integrate to regulate genes that ultimately govern behaviors. In
rodents, we study how estrogen signaling controls reproductive and social behaviors and how thyroid hormone signaling regulates mood as model systems to understand hormonal action.
Professor of Practice, Ph.D., University of Madras (India), 1994. Dr. Vijayaraghavan
teaches CELL 1010, General Biology, and CELL 2050, Genetics. Research interests
are in the areas of environmental carcinogenesis, cancer studies, and pediatric
nephrology. She has teaching and research experience in India, Japan, and the
US. She is interested in incorporating service learning in her biology courses.
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Cell and Molecular Biology, 2000 Percival Stern Hall, New Orleans, LA 70118 504-865-5546 firstname.lastname@example.org