Ph.D., 1980, Rice University
5092 Percival Stern Building
Organic Chemistry and Biochemistry
Areas of current interest
Dr. Pascal's principal research interests have been in the areas of biochemistry (enzyme mechanisms, design of enzyme inhibitors, and natural product biosynthesis) and physical organic chemistry (strained aromatic molecules, kinetic isotope effects, molecular association, and crystal engineering) with a recent emphasis on the latter.
Selected Recent Publications
1. Vavilala, C., N. Byrne, C. M. Kraml, D. M. Ho, and R. A. Pascal, Jr., Thermal C1-C5 Diradical Cyclization of Enediynes, J. Am. Chem. Soc. 2008, 130, 13549-13551.
2. Walters, R. S., C. M. Kraml, N. Byrne, D. M. Ho, Q. Qin, F. J. Coughlin, S. Bernhard, and R. A. Pascal, Jr., Configurationally Stable Longitudinally Twisted Polycyclic Aromatic Compounds, J. Am. Chem. Soc. 2008, 130, 16435-16441.
3. McQueen, T. M., D. M. Ho, C. Jimenez Cahua, R. J. Cava, R. A. Pascal, Jr., and Z. G. Soos, Realization of the bond order wave (BOW) phase of extended Hubbard models in Rb-TCNQ(II), Chem. Phys. Lett. 2009, 475, 44-48.
4. Qin, Q., J. T. Mague, and R. A. Pascal, Jr., An in-Ketocyclophane, Org. Lett. 2010, 12, 928-930.
5. Qin, Q., D. M. Ho, J. T. Mague, and R. A. Pascal, Jr., Exceptional Molecular Architectures via Cycloadditions to Pyrenequinones, Tetrahedron 2010, 66, 7933-7938.
6. Bai, X., C. Barnes, R. A. Pascal, Jr., X. Chen, and J. R. Dias, Bile Acid-Based Cage Compounds with Lipophilic Outer Shells and Inner Cavities, Org. Lett. 2011, 13, 3064-3067.
7. Kurtz, J., T. Grusenmeyer, L. Tong, G. Kosgei, R. H. Schmehl, J. T. Mague, and R. A. Pascal, Jr., Highly Luminescent, Polyaryl Mesobenzanthrones, Tetrahedron 2011, 67, 7211-7216.
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