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2009/09/08 - New Theoretical Approaches to Studying the Energetics and Dynamics of Complex Biomolecular Systems

Tulane University Center for Computational Science
is Sponsoring a Seminar on
New Theoretical Approaches to Studying the Energetics and Dynamics
of Complex Biomolecular Systems

This talk focuses on two important problems in theoretical biophysics: (1) How to study the dynamics of large biomolecular complexes like chromatin, and (2) how to extract intrinsic free energy barriers and kinetic rates of conformational transitions in biomolecules from single-molecule pulling experiments. In the first half of my talk, I will discuss a new mesoscopic modeling and simulation approach that provides fresh insights into the structure and dynamics of chromatin. In the second half of my talk, I will describe the development of a new analytical theory for extracting the intrinsic free energy barriers and rates of biomolecular transitions (e.g., RNA unzipping, protein unfolding) from rupture-force measurements in single-molecule pulling experiments.
Gaurav Arya
Assistant Professor, Department of Nanoengineering
University of California at San Diego
 
Tuesday, September 8, 2009
3:00pm
101 Stanley Thomas Hall
Tulane University (Uptown)
 
Refreshments will be served

Center for Computational Science, Stanley Thomas Hall 402, New Orleans, LA 70118 ccs@tulane.edu