Faculty

Michael J. Moore

Assistant Professor of Biomedical Engineering

Email: mooremj@tulane.edu
Phone: (504) 247-1919

Lindy Boggs Building
Department of Biomedical Engineering
Tulane University
New Orleans, LA 70118

Click to visit Dr. Moore's laboratory website

Education

University of Nebraska, Lincoln NE, 1999 B.S. Biological Systems Engineering
Mayo Clinic College of Medicine, Rochester MN, 2005 Ph.D. Biomedical Engineering
Massachusetts Institute of Technology, Cambridge MA,
The Schepens Eye Research Institute, Harvard Medical School, Boston MA, 2007 Post-doc

Research Interests

Our group utilizes tissue engineering and related technologies for the study of central nervous system (CNS) regeneration and development of treatments for CNS disorders. Our aim is to study how tissue architectural and microenvironmental factors affect neural axon growth and physiology in order to develop novel physiological models of neural tissue and to propose translational treatment strategies for neurological disorders. To investigate these phenomena, we are developing microscale technologies that make use of synthetic chemistry, materials science, micro-optoelectronics, microfabrication, optogenetics, computational modeling, and neurobiology.

Courses Taught

Fall: BMEN 3400/6400 - Biomaterials & Tissue Engineering
Fall: BMEN 3401/6401 - Biomaterials & Tissue Engineering Lab
Spring: BMEN 6260 - Molecular Princ of Functional Biomaerials

Honors and Awards

NSF Faculty Early Career Development (CAREER) Award, 2011
Alpha Eta Mu Beta Biomedical Engineering Teacher of the Year, 2009, 2011
Tulane Research Enhancement Fund Award, 2007
Ruth L. Kirschstein National Research Service Award (National Institutes of Health) 2003-2005

Selected Publications

http://www.researcherid.com/rid/E-9107-2011

Curley JL & Moore MJ. Facile micropatterning of dual hydrogel systems for 3D models of neurite outgrowth. J Biomed Mater Res A, 99(4):532-43, 2011.

Curley JL, Jennings SR, Moore MJ. Fabrication of micropatterned neural culture systems using dynamic mask projection photolithography. J Vis Exp, 48:e2636, 2011.

Krych AJ, Rooney GE, Chen B, Schermerhorn TC, Ameenuddin S, Gross L, Moore MJ, Currier BL, Spinner RJ, Friedman, JA, Yaszemski MJ, Windebank AJ. Relationship between scaffold channel diameter and number of regenerating axons in the transected rat spinal cord. Acta Biomater, 5(7):2551-9, 2009.

George PM, Saigal R, Lawlor MW, Moore MJ, LaVan DA, Marini RP, Selig M, Makhni M, Burdick JA, Langer R, Kohane DS. Three-dimensional conductive constructs for nerve regeneration. J Biomed Mater Res A, 91(2):519-27, 2009.

de Ruiter CG, Spinner RJ, Malessy MJA, Moore MJ, Sorenson EJ, Currier BL, Yaszemski MJ, Windebank AJ. Accuracy of motor axon regeneration across autograft, single lumen, and multichannel PLGA nerve tubes. Neurosurgery, 63(1):144-53, 2008.

de Ruiter CG, Onyeneho IA, Liang ET, Moore MJ, Malessy MJA, Spinner RJ, Lu L, Currier BL, Yaszemski MJ, Windebank AJ. Methods for in vitro characterization of multichannel nerve tubes. J Biomed Mater Res A, 84(3):643-651, 2008.

Jiang C, Moore MJ, Zhang X, Klassen H, Langer R, Young M. Intravitreal injections of GDNF-loaded biodegradable microspheres are neuroprotective in a rat model of glaucoma. Mol Vis, 13:1783-92, 2007.

Moore MJ, Friedman JA, Lewellyn EB, Mantila SM, Krych AJ, Knight AM, Lu L, Currier BL, Spinner RJ, Marsh RW, Windebank AJ, Yaszemski MJ. Multiple-channel scaffolds to promote spinal cord axon regeneration. Biomaterials, 27(3):419-29, 2006.

Moore MJ, Jabbari E, Ritman EL, Lu L, Currier BL, Windebank AJ, Yaszemski MJ. Quantitative analysis of interconnectivity of porous biodegradable scaffolds with micro-CT. J Biomed Mater Res A, 71A(2):258-67, 2004.

Talac R, Friedman JA, Moore MJ, Lu L, Jabbari E, Windebank AJ, Currier BL, Yaszemski MJ. Animal models for tissue engineering approaches to spinal cord injury. Biomaterials , 25(9):1505-10, 2004.

Friedman JA, Windebank AJ, Moore MJ, Spinner RJ, Currier BL, Yaszemski MJ. Biodegradable polymer grafts for surgical repair of the injured spinal cord. Neurosurgery , 51(3):742-52, 2002.