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Hypertension & Renal Center of Excellence
1430 Tulane Avenue
New Orleans, LA 70112
Phone: (504) 988-3703
Fax: (504) 988-2675




COBRE Pilot Projects

COBRE III Pilot Projects & Investigators

Each year, 3 investigators are awarded a one year $45,000 grant to support their research. Applications are subjected to a rigorous review process to ensure that funds are provided to only the most highly meritorious projects that are likely to lead to extramural research support and will stimulate multidisciplinary collaborative interactions. The following are names of Pilot Project award recipients and information on their pilot project. 



2014-2015 Pilot Project award recipients were T. Cooper Woods, Ph.D., Shaowei Chen, M.D., Ph.D., and Prerna Kumar, Ph.D.. The following were the three pilot projects:

  • Pilot Project 1:
    Non-coding RNA in Diabetes mediated Enhanced Intimal Thickening during Early Atherosclerotic Plaque Development.
    ~ PI: T. Cooper Woods, Ph.D.
  • Pilot Project 2:
    Histone Deacetylases 1 and 2 in Kidney Development
    ~ PI: Shaowei Chen, M.D., Ph.D. (August 1, 2014 till February 28, 2015)
    ~ PI: Hongbing Liu, Ph.D. (From March 1, 2015)
  • Pilot Project 3:
    Estrogen-dependent activation of guanylyl cyclase /natriuretic peptide receptor A gene expression via estrogen receptors ERα and ERβ.
    ~ PI: Prerna Kumar, Ph.D.

2013-2014 Pilot Project award recipients were Kenneth D. Mitchell, Ph.D.., Ryosuke Sato, Ph.D.., and Ihor V. Yosypiv, M.D. The following were the three pilot projects:

  • Pilot Project 1:
    PDGF Receptor Blockade Reverses the Renal Functional and Morphological Changes that occur in AngiotensinII-Dependant Hypertension.
    ~ PI: Kenneth D. Mitchell, Ph.D.
  • Pilot Project 2:
    Angiotensinogen Expression and Regulation in Renal Proximal Tubules during the Development of Angiotensin-II-Dependent Hypertension
    ~ PI: Ryosuke Sato, Ph.D.
  • Pilot Project 3:
    Prorenin Receptor in Collecting Duct Development.
    ~ PI: Ihor V. Yosypiv, M.D.

2012-2013 Pilot Project award recipients were Minolfa C. Prieto, M.D., Ph.D., Andrei V. Derbenev, Ph.D., and Zubaida Saifudeen, Ph.D. The following were the three pilot projects:

  • Pilot Project 1:
    Functional Role of ProRenin Receptor in the Collecting Duct to the Development of Hypertensionlar.
    ~ PI: Minolfa C. Prieto, M.D., Ph.D., Mentor: Dr. L. G. Navar.
  • Pilot Project 2:
    Role of p53 in Nephron Progenitor Cell Renewal and Differentiation
    ~ PI: Zubaida Saifudeen, Ph.D., Mentor: Dr. Samir S. El-Dahr.
  • Pilot Project 3:
    Regulation of inhibitory circuits in the RVLM by angiotensin II.
    ~ PI: Andrei V. Derbenev, Ph.D., Mentor: Dr. L. G. Navar.

Tulane University, New Orleans, LA 70118 504-865-5000