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Adjunct Faculty 

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Suresh C Sikka, PhD, HCLD

Suresh C Sikka, PhD, HCLD

Professor of Urology
Adjunct Associate Professor of Pharmacology and Biochemistry
Director of Andrology Clinic and Research Laboratories

Research Interests:
Molecular biology, differential gene expression, suppressive subtractive hybridization, other cell biology, biochemical, and chemiluminescence techniques

Dr. Sikka received his Ph.D. from the Department of Pharmacology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India, in 1978. He did his post-doctoral fellowship from 1979-1982 in the Department of Biochemistry at the University of Southern California (USC), Los Angeles where he obtained training in the field of protein-lipid interactions in cell membranes, protein purification, and functional incorporation into liposomes. In 1982 Dr. Sikka moved to the Urology section of the Department of Surgery at Harbor-UCLA Medical Center, University of California Los Angeles (UCLA), as Urology Laboratory Research Director. Dr. Sikka joined the Tulane faculty in 1989 as Assistant Professor of Urology and Andrology Laboratory Director. He was responsible for setting up a CLIA-approved Andrology Clinical and Research Laboratory at Tulane Medical Center, catering to the needs of many infertility and sexual dysfunction patients. Dr. Sikka's current research focus is oxidative stress-related signal transduction pathways and gene expression involved in prostate tumorigenesis (BPH and cancer) and drug targeting. The Urology department has recently procured a Laser Capture Microscope (LCM) to microdissect specific and selective biological cells from various clinical samples. LEQSF has also recently funded the Department to acquire the latest DNA - microarray system for expression of specific genes (genomics), and their translational products (proteonomics). The lab routinely employs molecular biology, differential gene expression, suppressive subtractive hybridization, other cell biology, biochemical, and chemiluminescence techniques as well as xenograft and transgenic models of disease and in situ studies on human tissues approaches to address many questions as they relate to prostate tumorigenesis. Using a super-repressor I kappa B adenoviral delivery approach, the lab plans to evaluate the role of inhibiting the activation of the nuclear factor NF-kappa B in enhancing radio/chemosensitization and apoptosis of prostate tumor cells. Analysis of the expression and function of these genes should allow for a more in depth understanding of the processes controlling prostate tumor growth, invasion and metastasis. The ultimate aim is on developing new diagnostic tools and potential therapeutic applications using a gene therapy approach (pharmacogenomics).


Sikka's Curriculum Vitae

Contact:
Suresh C. Sikka, PhD, HCLD
Department of Urology
1430 Tulane Avenue, SL-47
New Orleans, LA 70112
Office: (504)988-5179
Fax: (504)988-5059
ssikka@tulane.edu

1430 Tulane Ave, New Orleans, LA 70112 504-988-5263 medsch@tulane.edu