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TRANSPLANT SURGERY

Dr. Joseph F. Buell

Dr. Mary T Killackey

Dr. Anil S. Paramesh

Dr. Douglas P. Slakey



Ongoing Clinical Research Projects



  1. Integrated image-guided ultrasound ablation system for cancer management.; NIH (Dr.Buell)

  2. Composite Tissue Engineering; Department of Defense (Dr.Buell)

  3. A Phase 3, Double-Blind, Double-Dummy, Multi-Center, Prospective, Randomized Study of the Efficacy and Safety of LCP-Tacro™ Tablets, Once Daily, Compared to Prograf ® Capsules, Twice Daily, in Combination with Mycophenolate Mofetil for the Prevention of Acute Allograft Rejection in De Novo Adult Kidney Transplant Recipients; LifeCycle Pharma (Dr. Killackey and Dr. Buell)

  4. A Multi-Center, Randomized, Placebo-Controlled, Double-Blind Study to Confirm the Reversal of Hepatorenal Syndrome Type 1 with Lucassin® (Terlipression); Ikaria (Dr. Buell)

  5. Should Lymph Nodes Be Offered as Primary Crossmatch Material instead of Serum by OPOs; AOPO (Dr. Paramesh)

  6. Second generation mTOR inhibitors in new onset, post-transplant DM and as maintenance immunosuppression; Novartis (Dr. Slakey)


Transplant Faculty research interests

Dr. Buell

  • Advancing ablation technologies for the treatment of hepatocellular carcinoma
  • Medical reversal of hepatorenal syndrome
  • Tissue engineering

Dr. Killackey

  • The impact of Hep C in kidney transplant recipients and acute rejection events
  • Understanding acute rejection risk in long vs. short acting calcineurin inhibitors

Dr. Paramesh

  • The Impact of Hep C in kidney transplant candidates
  • The efficacy of lymph node vs. serum crossmatch assays

Dr. Slakey

  • The role of hyperbaric oxygen therapy in organ storage technology
  • Laparoscopic liver resections in for complex liver disease
  • Electrosurgery in complex liver and pancreas resections
  • HIV and solid organ transplantation
  • Advanced hemostatic modalities in liver resection


TRAUMA AND SURGICAL ICU

Dr. Juan Duchesne

Dr. Chrissy Guidry

Dr. Eric Simms

The Trauma and Surgical ICU is conducting clinical research in the fields of surgical resuscitation, blood transfusion and coagulation disorders.  Currently Dr. Guidry’s research is focused on examining the optimal blood product transfusion ratios in trauma settings and Dr. Simms’s research on the use of spinal immobilization in pre-hospital setting in penetrating trauma. The department is also working on a new Massive Transfusion Protocol to be used at Tulane HSC.

 


Recent research presentations


  • Duchesne J, Guidry C, Unruh M, Duke M, Meade P, McSwain N. Impact of Crystalloids to PRBC Ratio in Patients with exsanguinating Penetrating Abdominal Injuries: The Conundrum of Resuscitation. Journal of Trauma. August 2011 (Presented at Boston AAST 2010)

  • Duchesne J, Guidry C, Park T, Simms E, Hoffman J, Bock J, Meade P, Barbeau J, Wascom J, McSwain N. Impact of Low Fibrinogen Levels in the Puzzle of Trauma Induced Coagulopathy: Is this the Missing Link? Journal of Trauma. September 2011. (Presented at Chicago AAST 2011)

  • Duchesne J, Guidry C, Meade P, McSwain N. Intra-operative Close Ratio Resuscitation with Platelets Doesn’t Improve Survival in Patients with Trauma-Induced Coagulopathy. Injury. September 2011 (Presented at Boston AAST 2010)


ENDOCRINE SURGERY



Dr. Emad Kandil

Jingling Ma, PhD

Zak AbdelMageed, PhD

Salem Noureledine, MD



Xinying Li, MD, PhD


 


Basic science research projects


  • Targeting multiple cellular pathways in advanced thyroid cancer and identification of novel markers for thyroid cancer; Lousiana Cancer Research Consortium and Dean’s Fund (Dr. Kandil)


  • Molecular Profiling Analysis of Indeterminate Thyroid Nodule Fine Needle Aspirates to Determine Patterns Predictive of Benign or Malignant Disease; VERACYTE (Dr. Kandil)
 

Ongoing clinical research projects

  1. Staged vs. Total Thyroidectomy for Substernal Goiter

  2. Transaxillary Robotic Thyroidectomy: A Feasibility and Outcomes Study

  3. Outcome of robotic surgery in parathyroid, adrenal, and GI surgery

  4. Analysis of SEER database for role Impact of Extensive Neck Dissection on Survival from Papillary and Medullary Thyroid Cancer.

  5. Meta-analysis on different projects related to endocrine and oncological surgery including but not limited to predictors for Postoperative need for Hormone Replacement, need for surveillance and complications, effectiveness of radioactive iodine versus thyroidectomy in the treatment of Graves’ disease.



Tulane University, Department of Surgery, 1430 Tulane Ave. SL-22 New Orleans, LA 70112 504-988-5128 surgery@tulane.edu