L. Gabriel Navar, Ph.D.
Professor and Chair
Co-Director, Renal & Hypertension Center
Phone: (504) 988-2594
Room #: 4002

Email: navar@tulane.edu

PhD: University of Mississippi, 1966

Research Interests:

Research programs in Dr. Navar's laboratory investigate hormonal and paracrine mechanisms regulating renal hemodynamics, glomerular filtration rate (GFR), and sodium excretion. Intense activity is also focused on the pathophysiology of hypertension and the role of the intrarenal renin angiotensin system (RAS) in altering kidney function to lead to in angiotensin II dependent hypertension.

Laboratory Members:

• MingGuo Feng, MD – Research Scientist
• Alexis Gonzalez, PhD - Postdoctoral Fellow
• Catherine Howard – Graduate Student
• Daisuke Inui, PhD – Postdoctoral Fellow
• Ayumi Kitano, PhD – Lab Research Technician
• Marta Kuczeniska, PhD – Postdoctoral Fellow
• Kayoko Miyada, PhD – Postdoctoral Fellow
• Akemi Sato, PhD – Medical Research Specialist
• Ryo Sato, PhD – Research Scientist
• Dale Seth – Lab Supervisor
• Weijian Shao, PhD – Medical Research Specialist

Representative Publications:

1. Zhao D, Zhang J, Blaustein MP and Navar LG. Attenuated renal vascular responses to acute angiotensin II infusion in smooth muscle-specific Na+/Ca2+ exchanger knockout mice. Am J Physiol Renal Physiol 301: F574-F579, 2011.
2. Liu L, Gonzalez AA, McCormack M, Seth DM, Kobori H, Navar LG and Prieto MC. Increased Renin Excretion Associated with Augmented Urinary Angiotensin (Ang) II Levels in Chronic Angiotensin II-infused Hypertensive Rats. Am J Physiol Renal Physiol 301: F1195-F1201, 2011.
3. Gonzalez-Villalobos RA, Billet S, Kim C, Satou R, Fuchs S, Bernstein KE and Navar LG. Intrarenal Angiotensin-converting enzyme induces hypertension in response to Angiotensin I infusion. J Am Soc Nephrol 22: 449-459, 2011.
4. Lara LS, McCormack M, Semprum-Prieto LC, Shenouda S, Majid DS, Kobori H, Navar LG and Prieto MC. AT1 receptor-mediated augmentation of angiotensinogen, oxidative stress, and inflammation in ANG II-salt hypertension. Am J Physiol Renal Physiol 302: F85-F94, 2012.
5. Kobori H, Harrison-Bernard LM, Navar LG. Role of activated renin-angiotensin system in the pathogenesis of diabetic nephropathy. In: Prabhakar SS, editor. Advances in Pathogenesis of Diabetic Nephropathy. New York: Nova Science Publishers, Inc.; p. 161-97, 2012.
6. Green T, Gonzalez AA, Mitchell KD, Navar LG. The complex interplay between cyclooxygenase-2 and angiotensin II in regulating kidney function. Curr Opin Nephrol Hypertens 21:7-14, 2012.

Recent Publications: A PubMed listing of research publications for L. Gabriel Navar, Ph.D.

Contact:

Tulane University, School of Medicine,
Department of Physiology,
1430 Tulane Avenue, SL-39
New Orleans, LA 70112
Phone: 504-988-2594
Fax: 504-988-2675
Email: navar@tulane.edu