- Bacterial Pathogenesis
- Molecular aspects of the host-parasite relationship
- Vaccine Development
a great deal of effort has been directed towards replacement of
existing whole cell or formalin inactivated vaccines with subunit
vaccines that may be safer and more effective than existing vaccines.
Still other efforts are directed at developing alternatives to
traditional vaccine delivery, including mucosal and transcutaneous
Mucosally and transcutaneously delivered vaccines
offer a number of potential advantages over traditional vaccines
including 1) the potential to confer mucosal as well as systemic
immunity, 2) increased stability, 3) increased shelf-life, and 4)
elimination of needles and the need for specially trained healthcare
specialists to administer vaccines.
Dr. Clements's Vaccine
Research Laboratory is developing powerful new techniques for
vaccination against bacterial, viral, and parasitic diseases, including
novel adjuvants (substances that enhance the immune response to foreign
antigens) and delivery systems (nanocarriers for vaccine delivery).
John D. Clements, Ph.D.
Department of Microbiology & Immunology
Tulane University Health
1430 Tulane Avenue, SL-38
New Orleans, LA, 70112