Pulmonary Diseases, Critical Care, & Environmental Medicine

Articles

2011-2012 Academic Year Publications

Arsenic mediated disruption of promyelocytic leukemia protein nuclear bodies induces ganciclovir susceptibility in Epstein–Barr positive epithelial cells.
Sides MD, Block GJ, Shan B, Esteves KC, Lin Z, Flemington EK, Lasky JA.
Virology. 2011 Jul 20;416(1-2):86-97.

Epstein - Barr virus Latent Membrane Protein 1 suppresses reporter activity through modulation of Promyelocytic Leukemia Protein-Nuclear Bodies.
Sides MD, Block GJ, Chadwick RW, Shan B, Flemington EK, Lasky JA.
Virology Journal 2011, 8:461 (5 October 2011).

A Double blind, Placebo-Controlled, Randomized Trial of Combined Prednisone, Azathioprine and N-acetylcysteine in Idiopathic Pulmonary Fibrosis.
Raghu G, Anstrom KJ, King TE Jr, Lasky JA, Martinez FJ, on behalf of the IPFnet.
N Engl J Med. 2012 May 24;366(21):1968-77.

FTY720-induced conversion of conventional Foxp3- T cells to Foxp3+ regulators in NOD mice.   Wang W*, Sun Y*, Shan B*, Di J, Chen L, Ren L, Li D-J, Lin Y. 
Am J Reprod Immunol. 2011 Nov;66(5):349-362. (* denotes equal contribution)

Post-transcriptional Up-regulation of miR-21 by Type I Collagen. 
Li C, Nguyen HT, Zhuang Y, Lin Y, Flemington EK, Guo W, Guenther J, Burow ME, Morris GF, Sullivan D, Shan B.
Mol Carcinog. 2011 Jul;50(7):563-70.

Lung function, radiological changes and exposure: analysis of ATSDR data from Libby, MT, USA. Weill D, Dhillon G, Freyder , Lefante J, Glindmeyer H.
Eur Respir J. 2011 Aug;38(2):376-83.

The microRNA expression associated with morphogenesis of breast cancer cells in three-dimensional organotypic culture.
Nguyen HT, Li C, Lin Z, Flemington EK, Zhuang Y, Burow ME, Lin Y, Shan B.   
Oncol Rep. 2012 Jul;28(1): 117-126. Epub 2012 Apr 19.

Brain natriuretic peptide measurement in pulmonary medicine.
Salerno D, Marik PE.
Respir Med. 2011 Dec;105(12):1770-5. Epub 2011 Aug 6.

Randomized, placebo-controlled clinical trial of an aerosolized β₂-agonist for treatment of acute lung injury.
National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network (Simeone F listed in the appendix as one of the 188 collaborators), Matthay MA, Brower RG, Carson S, Douglas IS, Eisner M, Hite D, Holets S, Kallet RH, Liu KD, MacIntyre N, Moss M, Schoenfeld D, Steingrub J, Thompson BT.
Am J Respir Crit Care Med. 2011 Sep 1;184(5):561-8.

Enteral omega-3 fatty acid, gamma-linolenic acid, and antioxidant supplementation in acute lung injury.
Rice TW, Wheeler AP, Thompson BT, deBoisblanc BP, Steingrub J, Rock P; NIH NHLBI Acute Respiratory Distress Syndrome Network of Investigators (Simeone F  listed in the appendix as one of the 200 collaborators).
JAMA. 2011 Oct 12;306(14):1574-81. Epub 2011 Oct 5.

Initial trophic vs full enteral feeding in patients with acute lung injury: the EDEN randomized trial.
National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network (Simeone F listed in appendix as one of the 210 collaborators), Rice TW, Wheeler AP, Thompson BT, Steingrub J, Hite RD, Moss M, Morris A, Dong N, Rock P.  JAMA. 2012 Feb 22:307(8):795-803. Epub 2012 Feb 5.

Comparison of 3 different methods used to measure the rapid shallow breathing index. Desai NR, Myers L, Simeone F.
J Crit Care. 2012 Aug;27(4):418.e1-6. Epub 2011 Sep 29.

Free-Running Disorder in a Sighted Adolescent.
Endara-Bravo AS, Thammasitboon S, Thomas D.
J Pediatr. 2012 May;160(5):877. Epub 2012 Jan 9.

Activation of autophagy in mesenchymal stem cells provides tumor stromal support. Sanchez CG, Penfornis P, Oskowitz AZ, Boonjindasup AG, Cai DZ, Dhule SS, Rowan BG, Kelekar A, Krause DS, Pochampally RR.
Carcinogenesis. 2011 Jul;32(7):964-72. Epub 2011 Feb 11.

2010-2011 Academic Year Publications

B Shan, JS Hagood, Y Zhuo, DR Levy, and JA Lasky. Thy-1 regulates TNF-alpha stimulated matrix metalloproteinase 9 expression in fibroblasts via src family kinase, PLoS One. 2010 Jul 19;5(7):e11662.

M Sides^1,4, R Klingsberg^2,4, B Shan³,K Gordon², H Nguyen¹, E Flemington³, JA Lasky^2,5. The Epstein-Barr virus LMP 1 and TGFb1 synergistically induce EMT in human alveolar epithelial cells, Am J Respir Cell Mol Biol. 2010 Aug 6.

X Yue, B Shan, JA Lasky. TGF-b: Titan of Lung Fibrogenesis. Current Enzyme Inhibition 2010 6(2):67-77. (Review).

J. Guenther, J Cameron, H. Nguyen, Y. Wang, D. Sullivan, B. Shan, JA Lasky, E. Flemington, and G. Morris. Modulation of Lung Inflammation by the Epstein-Barr Virus Protein Zta, Am J Physiol Lung Cell Mol Physiol. 2010 Dec;299(6):L771-84. Epub 2010 Sep 3.

Raghu G, Collard HR, Egan JJ, Martinez FJ, Behr J, Brown KK, Colby TV, Cordier JF, Flaherty KR, Lasky JA, Lynch DA, Ryu JH, Swigris JJ, Wells AU, Ancochea J, Bouros D, Carvalho C, Costabel U, Ebina M, Hansell DM, Johkoh T, Kim DS, King TE Jr, Kondoh Y, Myers J, Müller NL, Nicholson AG, Richeldi L, Selman M, Dudden RF, Griss BS, Protzko SL, Schünemann HJ; on behalf of the ATS/ERS/JRS/ALAT Committee on Idiopathic Pulmonary Fibrosis. An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management. Am J Respir Crit Care Med. 2011 Mar 15;183(6):788-824.

Svitlana Danchuk, Joni H Ylostalo, Fokhrul Hossain, Randy Sorge, Austin Ramsey, Ryan W Bonvillain, Joseph A Lasky, Bruce A Bunnell, David A Welsh, Darwin J Prockop and Deborah E Sullivan. Human Multipotent Stromal Cells Attenuate LPS-Induced Acute Lung Injury in Mice via Secretion of TNF-alpha-induced Protein 6. Stem Cell Res Ther. 2011 May 13;2(3):27.

S, LaskyJA, GuoW, NguyenHT, MaiA, Danchuk FS, SullivanDE, ShanB. Pharmacological Inhibition of HDAC6 Attenuates Endothelial Barrier Dysfunction Induced by Thrombin. Biochem Biophys Res Commun. Biochem Biophys Res Commun. 2011 May 20;408(4):630-4.

Sanchez C, Penfornis P, Oskowitz AZ, Boonjindasup AG, Cai DZ, Dhule S, Rowan BG, Kelekar A, Krause DS and Pochampally R. Activation of Autophagy in Mesenchymal Stem Cells Provides Tumor Stromal Support. Carcinogenesis (2011) First published online: February 11, 2011.

Mishur RJ, Griffin ME, Battle C, Shan B, and Jayawickramarajah J. Molecular Recognition and Enhancement of Solubility and Bioactivity of CD437 by b-Cyclodextrin. Bioorg Med Chem Lett. 2011 Jan 15;21(2):857-60.

Lin Y*, Li C*, Shan B*, Wang W, Di J, Zhong Y, Li D. Reduced Expression of Stathmin-1 in NK Cells Associated with Spontaneous Abortion. Am J Pathol. 2011 Feb;178(2):506-14. (* denotes equal contribution)

Yin G, Li C, Shan B, Wang W, Chen H, Zhong Y, Di J, Lin Q, Lin Y. Insufficient Peroxiredoxin-2 Expression in Uterine NK Cells Obtained from a Murine Model of Abortion. J Cell Biochem. 2011 Mar;112(3):773-81. PMID: 21328451

Li C, Nguyen HT, Zhuang Y, Lin Y, Flemington EK, Guo W, Guenther J, Burow ME, Morris GF, Sullivan D, Shan B. Post-transcriptional Up-regulation of miR-21 by Type I Collagen. Mol Carcinog. 2011 Jul;50(7):563-70. PubMed PMID: 21647970.

Wang W*, Sun Y*, Shan B*, Di J, Chen L, Ren L, Li D-J, Lin Y. FTY720-induced conversion of conventional Foxp3- T cells to Foxp3+ regulators in NOD mice. Am J Reprod Immunol. 2011 May 27. [Epub ahead of print] PubMed PMID: 21623989. (* denotes equal contribution)

Anbalagan M, Carrier L, Glodowski S, Hangauer D, Shan B, Rowan BG. KX-01, a novel Src kinase inhibitor directed toward the peptide substrate site, synergizes with tamoxifen in estrogen receptor α positive breast cancer. Breast Cancer Res Treat. 2011 Apr 21. [Epub ahead of print] PubMed PMID: 21509526.

Weill D, Dhillon G, Freyder L, Lefante J, Glindmeyer H. Lung function, radiological changes and exposure: analysis of ATSDR data from Libby, MT, USA. Eur Respir J. 2011 Aug;38(2):376-83. Epub 2010 Dec 22.

2009-2010 Academic Year Publications

Klingsberg, RC, Mutsaers S and Lasky JA. Current clinical trials for the treatment of idiopathic pulmonary fibrosis. Respirology (2010) vol. 15 (1) pp. 19-31

Guo, W, Shan, B, Klingsberg, RC, Qin, X, Lasky, J. Abrogation of TGF-β1-induced Fibroblast-Myofibroblast Differentiation by Histone Deacetylase (HDAC) Inhibition. American journal of physiology Lung cellular and molecular physiology (2009) pp. L864-70.

Yue X, Shan B and Lasky JA. (2010) TGF-b: Titan of Lung Fibrogenesis. Current Enzyme Inhibition (Invited review, in press)

Zhuang Y, Nguyen HT, Lasky JA, Cao S, Li C, Hu J, Guo X, Burow ME, Shan B. Requirement of a Novel Splicing Variant of Human Histone Deacetylase 6 for TGF-b1-mediated Gene Activation. Biochem Biophys Res Commun. 2010 Feb 19;392(4):608-13.

King TE Jr, Albera C, Bradford WZ, Costabel U, Hormel P, Lancaster L, Noble PW, Sahn SA, Szwarcberg J, Thomeer M, Valeyre D, du Bois RM; INSPIRE Study Group (Lasky JA). Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): a multicentre, randomised, placebo-controlled trial. Lancet. 2009 Jul 18;374(9685):222-8. Epub 2009 Jun 29.

Craig E. Daniels & JA. Lasky & Andrew H. Limper, Kathleen Mieras, Edith Gabor, Darryl Schroeder, Imatinib Treatment for IPF: Randomized Placebo Controlled Trial Results . Am J Respir Crit Care Med. 2010 Mar 15;181(6):604-610. Epub 2009 Dec 10.

National Heart, Lung and Blood Institute Idiopathic Pulmonary Fibrosis Clinical Trial Research Network (IPFnet (Lasky JA)), A controlled trial of sildenafil in advanced idiopathic pulmonary fibrosis, NEJM May 18, 2010.

Dane. Nichols, Nathan D. Nielsen. Oxygen Delivery and Consumption: A Macrocirculatory Perspective Critical Care Clinics, Volume 26, Issue 2, Pages 239-253

Chisholm R, Thammasitboon S. A link between obstructive sleep apnea and erectile dysfunction: Myth or fact? Louisiana Academy of Sleep Medicine (LASM) 3rd Quarter Newsletter, September 2009.

Gur S, Kadowitz PJ, Thammasitboon S, Lasky JA, Hellstrom WJ. Characterization of erectile function in monocrotaline-treated pulmonary hypertensive rats. J Androl. 2009 Sep-Oct;30(5):495-504.

Right pulmonary artery agenesis presenting with uncontrolled asthma in an adult: a case report. Hafez M Hayek, Jaime Palomino, Supat Thammasitboon. Cases Journal. In Press.

Coccidioidomycosis in nonendemic area: case series and review of literature. Neeraj Desai, Robin McGoey, Dana Troxclair, Francesco Simeone and Jaime Palomino. Journal of the Louisiana State Medical Society. J La State Med Soc. 2010;162:97-103.

A 67-year-old woman with a remote history of breast cancer who presents with dyspnea and chest pain. Neeraj Desai, Jaime Palomino, and Francesco Simeone. Chest. 2009;136:1160-1163.

Mohan, K, Simeone, F and Parada, N A 79- year-old Man With Chest Wall Pain and A Rapidly Growing Mass Chest 2009; 135:221-4

Hollingsworth HM, Parada NA. Anaphylaxis Manual of Intensive Care Medicine. 5th edition. Ed. Richard S. Irwin MD and James M. Rippe MD Lippincott Williams. 2009.

Palomino J, Saeed O, Daroca P, Lasky J.A., 47-year-old man with cough, dyspnea, and an abnormal chest radiograph. Chest. 2009 Mar; 135(3):872-5

Salerno D, Sarcoidosis pleural effusion: a not so common feature of a well known pulmonary disease. Respir Care. 2010 Apr;55(4):478-80.

Salerno D, Marik PE, Daskalakis C, Kolm P, Leone F. The role of head computer tomographic scans on the management of MICU patients with neurological dysfunction. J Intensive Care Med. 2009 Nov-Dec;24(6):372-5.

Clinical trials, case reports, etc.

National Heart, Lung and Blood Institute Idiopathic Pulmonary Fibrosis Clinical Trial Research Network (IPFnet), A controlled trial of sildenafil in advanced idiopathic pulmonary fibrosis, N Engl J Med. 2010 Aug 12;363(7):620-8. - Lasky

Noble PW, Albera C, Bradford WZ, Costabel U, Glassberg MK, Kardatzke D, King TE Jr, Lancaster L, Sahn SA, Szwarcberg J, Valeyre D, du Bois RM; CAPACITY Study Group. Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials. Lancet. 2011 May 21;377(9779):1760-9. Epub 2011 May 13. – Lasky

A 63-Year-Old Man With Recurrent Pulmonary Infections: A case of Swyer-James Macleod Syndrome. Neeraj Desai, Jaime Palomino, Hafez Hayek, Jay Shames and Francesco Simeone. J. La State Med Soc. 2010;162:346-349.

Coccidioidomycosis in nonendemic area: case series and review of literature.  Neeraj Desai, Robin McGoey, Dana Troxclair, Francesco Simeone and Jaime Palomino. J La State Med Soc. 2010;162:97-103.

Low-dose tissue plasminogen activator in pulmonary embolism: benefit remains unclear. =""=""> S, Altaqi B, Simeone F. (Letter to the editor) Chest. 2011 Feb;139(2):479-80.