Biochemistry & Molecular Biology

Positions » Postdoc

Postdoctoral Position:  POSTDOCTORAL FELLOW  (04/29/13)

A postdoctoral research position is available to study the role of Gas6/Axl signaling in breast cancer progression. Specifically, unique p53-null mouse model will be used to delineate the mechanisms by which inflammatory macrophages promote switch from premalignant DCIS (ductal carcinoma in situ) to invasive breast cancer. In addition, novel DCIS xenograft models will be employed to delineate signaling pathways in vivo. The long-term goal of this project is identify receptor tyrosine kinase receptors and/or chemokine receptors as potential therapeutic targets in the prevention of breast cancer progression.

MINIMUM QUALIFICATIONS REQUIRED:

• Ph.D.
• Research experience in the areas of cell culture, cell-based assays, RNA and protein analysis, and basic molecular biology techniques. Preference will be given to candidates with experience and knowledge in the fields of stem cell biology, mammary gland biology, and cancer biology, and research experience with animal models, including mammary gland.
• Ability to work independently on projects, including experimental design, execution, problem solving, data analysis, and data interpretation.
• Ability to critically review the scientific literature, write and review manuscripts, and present data to the scientific community. 
  

Interested applicants should provide their CVs to Heather Machado at hmachado@tulane.edu.

Postdoctoral positions to study the ribosomal stress-MDM2-MDMX-p53 pathway in cancer development and prevention.

MINIMUM QUALIFICATIONS REQUIRED: (Education, experience, skills, etc.)

• Ph.D. or M.D.
• Experience in the areas of protein biochemistry, purification, structural biology, animal genetic, genotyping, tissue dissection immunohistochemistry (IHC), cell-based assays including WB, co-IP, cell proliferation/growth, apoptosis, immunofluorescence staining, real-time PCR, molecular cloning, transgenic mouse and xenograft tumor mouse models.
• Able to semi-independently work on projects including experimental design, execution, problem solving, data analysis, draft a manuscript and write review articles as well as book chapters under the supervision of the PI in the lab.
• Able to review journal manuscripts and provide critiques and able to orally present primary and published results in lab meetings as well as in conferences.

Interested applicants should provide their CVs to Hua Lu, MD, Ph.D., Professor and Chair at hlu2@tulane.edu.