Students will participate in close association with their preceptor in ongoing research activities.
1. Renal and Vascular Physiology and Pathophysiology of Hypertension
Dr. L.G. Navar office: room 4002, SOM phone: 988-5252 e-mail: email@example.com
Dr. K. D. Mitchell office: room 4055, SOM phone: 988-2593 e-mail: firstname.lastname@example.org
Dr. D. Majid office: room 4020, SOM phone: 988-2600 e-mail: email@example.com
Dr. M. Prieto office: room 4061, SOM phone: 988-2445 e-mail: firstname.lastname@example.org
Several faculty members, led by our Chairman, Dr. L.G. Navar, are investigating the role of the kidney and blood vessels in the pathophysiology of hypertension. Students will be exposed to various experimental approaches used in the study of renal function, hemodynamics, tubular transport processes, and fluid and electrolyte regulation. Student can learn techniques for the evaluation of renal function, renal tubule reabsorption, and vascular responses to different antihypertensive drugs, as well as the expression and regulation of genes involved in hypertension. Basic methodological approaches also will be covered in a systematic manner. The remainder of the student's time will be spent in one or more laboratories of participating faculty.
2. Molecular Physiology of Signal Transduction in Hypertension and Cardiovascular Regulation
Dr. K. Pandey office: room 4022, SOM, phone: 988-1628; e-mail: email@example.com
Dr. Pandey’s laboratory is studying the role of vasoactive natriuretic peptide hormones and their receptors in the pathophysiology of hypertension and cardiovascular regulation. The ongoing studies include: molecular cloning and site-directed mutagenesis, gene transcription and expression, and cGMP-dependent transmembrane signaling mechanisms. The student will be exposed to a number of modern cellular and molecular approaches to delineate the genetic basis of hypertension and cardiovascular disorders both in vitro using cell culture systems and in vivo using gene-targeted mouse models
3. Cardiovascular Physiology – Cardiovascular Complications of Diabetes Mellitus and Chronic Kidney Disease
Dr. C. Woods office: room 4008, SOM; phone: 988-2588; email: firstname.lastname@example.org
Dr. Woods’ research aims to elucidate the impact of co-morbidities such as Diabetes Mellitus and Chronic Kidney Disease on the progression of cardiovascular disease. A focus of this research is toward understanding the molecular mechanisms underlying the increased intimal thickening seen in the diabetic population. These studies are currently examining the how the presence of diabetes promotes the acceleration of vascular smooth muscle cell proliferation and migration, two components of intimal thickening, through increases in specific microRNAs. Additional projects focus on the development of biomarkers for the identification of patients at high risk for cardiovascular disease and complications following angioplasty.
4. Cellular Signaling Physiology
Dr. M. Li office: room M728 SOM, phone: 988-8207; e-mail: email@example.com
Dr. Li’s research is focused on the cellular signaling mechanisms of insulin secretion and cancer cell proliferation. In particular, Dr. Li is studying intracellular calcium signaling and the role of calcium ion channels in the progression of diabetes mellitus and breast and prostate cancer. Students will employ fluorescence imaging and patch clamp techniques to investigate the role of calcium ion channels in hormone secretion and in cell proliferation.
5. Neurophysiology – synaptic organization of the central nervous system
Dr. A Derbenev office: room 4012 phone: 988-2053 email: firstname.lastname@example.org
Dr. A. Zsombok office: room 4010 phone: 988-2597 email: email@example.com
Dr. Derbenev and Dr. Zsombok are investigating the mechanisms that specify the identity of neurons and neuronal networks, involved in the sympathetic and parasympathetic regulation of visceral organs. They are using patch-clamp whole-cell electrophysiological, immunochemical, neuropharmacological, and molecular biological techniques.
Dr. Zsombok is studying the role of the central nervous system in the regulation of glucose metabolism and the dysregulated brain-liver circuit during diabetic conditions.
Dr. Derbenev is studying synaptic organization and regulation of synaptic activity in areas of the brain and spinal cord which are involved in blood pressure regulation.
Please see individual faculty members directly or contact Dr. Kenneth D. Mitchell, Overall Coordinator
Email: firstname.lastname@example.org Phone: (504) 988-2593 Fax: (504) 988-2675
Mailing Address: 1430 Tulane Ave., SL-39, New Orleans, LA 70112
Enrollment: 1-8 students; T-1, T-2, T-4
Time of course: 4-8 hours per session for 2 sessions: Wednesday and/or Friday: 1:00-5:00 p.m.
Sessions 1 and 2, Sessions 3 and 4
Prerequisite: Instructor's approval and brief prospectus.
1430 Tulane Ave, New Orleans, LA 70112 504-988-8070 email@example.com