The People of Tulane Cancer Center Research
Chang Han, M.D., Ph.D.
Han C, Lim C, Li GY, et al. Transgenic expression of of cyclooxygenase-2 in hepatocytes accelerates endotoxin-induced acute liver failure. J. Immunol. 2008, 181(11):8027-8035.
Han C, Lim K, Xu LH, et al. Regulation of Wnt/beta-catenin pathway by cPLA2alpha-mediated PPARdelta activation. J. Cell. Biochem 2008, 105 (2): 534-545.
Han C, Demetris AJ, Stolz D, et al. Modulation of Stat-3 activation by the cPLA2alpha and COX-2 controlled PGE2 signaling pathway. J. Biol. Chem. 2006, 281(34):24831-24846.
Han C and Wu T. Cyclooxygenase-2-derived prostaglandin E2 promotes human cholangiocarcinoma cell growth and invasion through EP1 receptor-mediated activation of the epidermal growth factor receptor and Akt. J. Biol. Chem. 2005, 280(25):24053-24063.
Han C, Demetris AJ, Liu Y, et al. TGF-beta activates cPLA2alpha-mediated PGE2/EP1 and PPAR-gamma/Smad signaling pathways in human liver cancer cells: a novel mechanism for subversion of TGF-beta-induced mitoinhibition. J. Biol. Chem. 2004, 279(43): 44344-44354.
Han C, Leng J, Demetris AJ, et al. Cyclooxygenase-2 promotes human cholangiocarcinoma cell growth: evidence for cyclooxygenase-2 independent mechanism in celecoxib-mediated induction of p21waf1/cip1 and p27kip1 and cell cycle arrest. Cancer Res. 2004, 64:1369-1376.
Han C, Demetris AJ, Michalopoulos GK, et al. PPARgamma ligands inhibit cholangiocarcinoma cell growth through p53-dependent GADD45 and p21waf1/cip1 pathway. Hepatology 2003, 38:167-177.
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