Master of Science in Clinical Research
Roy S. Weiner, MD
Dr. Roy Weiner is the Schlieder Professor of Medical Oncology and Associate Dean for Clinical Research and Training at Tulane University School of Medicine. and also serves as Director of the MS-CR Program. Dr. Weiner trained at the NCI, at the Institut for Cancerologie et d'Immunogenetique in Villejuif under Prof. Georges Mathe, and at Harvard. His laboratory research focused on stem cell physiology and cryobiology of lymphoid and stem cell populations. He has enormous experience in designing and executing small translational clinical trials, large prospective randomized therapeutic trials, and the analysis of large registry databases. Prior to joining Tulane as the founding Director of the Tulane Cancer, he directed cancer activities as PI of the NCI-funded Cancer Center Planning Grant at the University of Florida. During his tenure as Program Director at the University of Florida, he was responsible for the training of 29 medical oncologists, 14 of whom currently hold full-time academic positions on the faculty of major medical schools. He was also the laboratory preceptor for eight trainees who are now full-time academicians and have independent research programs. He has served the NIH as Chairman of the Clinical Sciences Study Section (NRSA), and was a member of the Clinical Program Project Study Section and the CCIRC. Dr. Weiner serves as the Course Director for Protocol Writing and Design, Topics in Clinical Research and Journal Club.
Paula Gregory, Ph.D
Dr. Gregory is a full professor with appointments in the Departments of Genetics and Cell Biology and Anatomy at LSUHSC-New Orleans, as well as an adjunct appointment at Tulane University. She is the Co-Director of the Tulane MSCR program and the Co-Director of the Louisiana Clinical and Translational Science Clinical Research Education, Mentoring and Career Development Core.
Her PhD research was carried out at Tulane University on cancer cytogenetics. For her postdoctoral training, she worked with Dr. Bill Brinkley at the University of Alabama at Birmingham and did further training with Dr. Francis Collins at the University of Michigan. While at U of M, she started the first Education Program within a Human Genome Center. In 1993, she started the Genetics Education Office of the National Institute for Human Genome Research within the National Institutes of Health, as a national extension of her work at U of M. While at the NIH, she started several new and innovative educational programs for the media, policy makers, students, faculty and the public. These efforts earned her the NHGRI Award of Merit (1994), NIH Director's Award (1997), the NIH Award of Merit (1998) and the Champions of the James Award (2000). She accepted a faculty position at the Ohio State University in 1997 and began research focused on cancer genetics education. In 2002 Dr. Gregory joined the Department of Genetics at Louisiana State University Health Sciences Center as an Associate Professor. Dr. Gregory was awarded the Copping Award for Excellence in Education in 2013, this award is voted on by both the medical students and the faculty and is the highest teaching award the university gives.
Dr. Gregory is also the Director of the Office of Faculty Development for the School of Medicine. In that role, she works with new faculty and fellows to facilitate their career transition and ensure their career success. Faculty Development includes on-boarding, New Faculty Orientation and continued research and career development support throughout the initial years of their appointment.
She has been awarded three NIH T35 Short Term Training Program grants (from NHLBI, NIDDK and NIAAA) to support medical student summer research. She also has funding from the American Heart Association to fund medical student research. Dr. Gregory is the Principal Investigator for an NIH R25 grant (NIAAA) that funds undergraduate and high school student research training. Along with collaborators at Ochsner, she has been awarded an NIH R25 Science Education Partnership Award to fund a program targeting the science teachers in the greater New Orleans area.
Dr. Gregory teaches in several graduate level courses, including two courses that she created Proposal Writing and Responsible Conduct of Research. She also helped create a genetics course for nursing students, Genetics Throughout the Lifespan and the Clinical Genetics course for the new LSUHSC Physician Assistant's Program.
Dr. Gregory is a member of several School of Medicine committees, including: the Women's Affairs Committee, the Faculty Development and Evaluation Committee, the Research Advisory Committee, the Student Promotions Committee and the Junior Faculty Guidance and Mentoring Committee. Dr. Gregory serves as the Course Director for Responsible Conduct of Research and Grant Writing.
Tong Wu, M.D., Ph.D
Dr. Wu’s basic research centers on the molecular mechanisms of inflammation and carcinogenesis, with a special emphasis on the pathogenesis of liver cancer and inflammatory liver diseases. The laboratory focuses on the biological functions and molecular mechanisms of arachidonic acid/prostaglandin and other key signaling pathways in hepatobiliary cell biology, inflammation and carcinogenesis. Arachidonic acid metabolites, termed eicosanoids (including prostaglandins, leukotrienes and HETEs), are potent biologically active molecules in inflammation and carcinogenesis. They mediate a variety of cellular physiological and pathophysiological functions through binding to their plasma membrane receptors and/or nuclear transcription factors (PPARs). Whereas the pro-inflammatory and carcinogenic eicosanoids are synthesized from arachidonic acid (an omega-6 polyunsaturated fatty acid), this process is competitively inhibited by omega-3 polyunsaturated fatty acids. The production of arachidonic acid metabolites is tightly controlled by a series of enzymes including cytosolic phospholipase A2 (cPLA2), cyclooxygenase-2 (COX-2), microsomal prostaglandin E synthase-1 (mPGES-1), and 15-hydroxyprostaglandin dehydrogenase (15-PGDH). Dr. Wu’s laboratory is actively investigating the interaction between the eicosanoid cascade with other signaling pathways (including TGF-b, EGFR, iNOS and Wnt/b-catenin) and their role in liver injury, inflammation and carcinogenesis. A variety of in vitro and in vivo model systems are being utilized to study key eicosanoid-regulatory enzymes, eicosanoid receptors (G protein coupled receptors and PPARs), omega-3 fatty acids, microRNAs, TGF-b, EGFR, iNOS, Wnt/b-catenin, and Hedgehog signaling pathways in liver cells. The laboratory also investigates liver cancer epigenetics, mechanisms of liver injuries, and growth regulation of hepatocytes and biliary epithelial cells. Dr. Wu also conducts active clinical research on transplantation pathology, primarily in liver and intestine transplantation. Dr. Wu serves as the Course Director for Molecular Medicine.
Gilbert Morris, Ph.D.
After receiving his B.S. (cum laude) in Chemistry from the University of Georgia in 1975, Dr. Morris worked for one year as a research technician at Sylvachem, a natural products research and development lab. He entered graduate school in the Organic Chemistry Division of the Chemistry Department at Florida State University in 1976. After one year in graduate school, he switched to the Biochemistry Division where he studied small RNA synthesis during sea urchin development with Dr. W. F. Marzluff. He obtained his Ph.D. in 1982 and performed post-doctoral training with Dr. Marzluff before accepting a post-doctoral position in 1985 with Dr. E. S. Weinberg at the University of Pennsylvania where he studied histone biosynthesis during sea urchin development. In 1986, Dr. Morris accepted a post-doctoral fellowship from the Arthritis Foundation to work on autoimmunity with Dr. M. B. Mathews at Cold Spring Harbor Laboratory. Upon receiving a NIH post-doctoral fellowship in 1987, Dr. Morris changed the focus of his project to regulation of proliferating cell nuclear antigen (PCNA), a DNA replication and repair protein. Dr. Morris maintained his interest in regulation of PCNA expression while he was promoted to Staff Associate in 1989 and Staff Investigator in 1992 at Cold Spring Harbor Laboratory. He came to an Assistant Professor position in the Department of Pathology at Tulane University in 1993 and began work in lung biology. He reached the academic rank of Associate Professor in 1999. His current research focus is on the molecular mechanisms of lung disease induced by inhaled toxins such as cigarette smoke and asbestos. His current findings support the concept that chronic Th17 inflammation promotes progression of lung adenocarcinoma. Dr. Morris serves as the Course Director for Therapeutics Seminar.
Eboni G. Price-Haywood, M.D., M.P.H.
Eboni Price-Haywood, M.D., M.P.H., F.A.C.P., is the former director of the Brinton Family Health and Healing Center and former medical director (2005-2014) for the Tulane Community Health Centers. She is now the director of the Center for Applied Health Services Research at Ochsner Health Systems and the Ochsner Primary Care Research Network. Dr. Price-Haywood received her Bachelor of Science from the University of Notre Dame in 1995, her medical degree from the Johns Hopkins University School of Medicine in 1999, and a Master of Public Health from the Johns Hopkins Bloomberg School of Public Health in 2004. She also completed a three-year fellowship in medical education and research at Johns Hopkins in 2005. Dr. Price-Haywood has distinguished herself over the last nine years with her achievements in health service delivery re-design and population health management. She provided community leadership in health information exchange to improve transitions of care, disease care management, and health prevention as chair of the Clinical Ql Subcommittee for the Greater New Orleans Health Information Exchange (2012-2014). She is now a co-investigator for the Louisiana Clinical Data Research Network (LA-CDRN) and member of the PCORnet Patient and Consumer Engagement Task Force. Her current research interest is deciphering which aspects of the patient-centered medical home drives improvement in health outcomes to inform providers of the most cost-effective strategies. Dr. Price-Haywood serves as the course director for Cultural Competence in Healthcare.
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