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 Jiang He    

Jiang He, MD
Joseph S. Copes Chair and Professor
Department of Epidemiology
Tulane University School of Public Health and Tropical Medicine
1440 Canal Street, Suite 2000
New Orleans, LA 70112
Phone: (504) 988-5165
Fax: (504) 988-1568
jhe@tulane.edu

Curriculum Vitae 



Research Interests:

Cardiovascular and genetic epidemiology; clinical trials; global health 

 

Educational Background:

  • PhD, Johns Hopkins School of Hygiene and Public Health, Baltimore, Maryland
  • DrMedSc, Peking Union Medical College, Beijing, PR China
  • MD, Jiangxi Medical College, Jiangxi, PR China

Professional Achievements:

  • Delta Omega Society, 2001
  • President's Award for Excellence in Research of Tulane University, 2000
  • Phi Beta Kappa, 1997
  • NIH-NHLBI Post-Doctoral Training Grant in Cardiovascular Disease Epidemiology, 1994-96
  • Jeremiah Stamler New Investigator Award of the American Heart Association, Finalist, 1993, 1994

Selected Publications:

Kelly TN, Takeuchi F, Tabara Y, Edwards TL, Kim YJ, Chen P, Li H, Wu Y, Yang CF, Zhang Y, Gu D, Katsuya T, Ohkubo T, Gao YT, Go MJ, Teo YY, Lu L, Lee NR, Chang LC, Peng H, Zhao Q, Nakashima E, Kita Y, Shu XO, Kim NH, Tai ES, Wang Y, Adair LS, Chen CH, Zhang S, Li C, Nabika T, Umemura S, Cai Q, Cho YS, Wong TY, Zhu J, Wu JY, Gao X, Hixson JE, Cai H, Lee J, Cheng CY, Rao DC, Xiang YB, Cho MC, Han BG, Wang A, Tsai FJ, Mohlke K, Lin X, Ikram MK, Lee JY, Zheng W, Tetsuro M, Kato N, He J. Genome-Wide Association Study Meta-Analysis Reveals Transethnic Replication of Mean Arterial and Pulse Pressure Loci. Hypertension. 2013 Sep 3.

Zhao Q, Gu D, Chen J, Li J, Cao J, Lu F, Guo D, Wang R, Shen J, Chen J, Chen CS, Mills KT, Schwander K, Rao DC, He J. Blood Pressure Responses to Dietary Sodium and Potassium Interventions and the Cold Pressor Test: The GenSalt Replication Study in Rural North China. Am J Hypertens. 2013 Sep 4.

Rebholz CM, Reynolds K, Wofford MR, Chen J, Kelly TN, Mei H, Whelton PK, He J. Effect of soybean protein on novel cardiovascular disease risk factors: a randomized controlled trial. Eur J Clin Nutr. 2013 Jan;67(1):58-63

He J, Reilly M, Yang W, Chen J, Go AS, Lash JP, Rahman M, DeFilippi C, Gadegbeku C, Kanthety R, Tao K, Hamm LL, Ojo A, Townsend R, Budoff M; CRIC Investigators. Risk factors for coronary artery calcium among patients with chronic kidney disease (from the Chronic Renal Insufficiency Cohort Study). Am J Cardiol. 2012 Dec 15;110(12):1735-41.

Kelly TN, Rebholz CM, Gu D, Hixson JE, Rice TK, Cao J, Chen J, Li J, Lu F, Ma J, Mu J, Whelton PK, He J. Analysis of Sex Hormone Genes Reveals Gender Differences in the Genetic Etiology of Blood Pressure Salt Sensitivity: The GenSalt Study. Am J Hypertens. 2013 Feb;26(2):191-200. doi: 10.1093/ajh/hps018. Epub 2012 Dec 28.

Mills KT, Kobori H, Hamm LL, Alper AB, Khan IE, Rahman M, Navar LG, Liu Y, Browne GM, Batuman V, He J, Chen J. Increased urinary excretion of angiotensinogen is associated with risk of chronic kidney disease. Nephrol Dial Transplant. 2012 Aug;27(8):3176-81. doi: 10.1093/ndt/gfs011. Epub 2012 Mar 6.

Mei H, Chen W, Mills K, He J, Srinivasan SR, Schork N, Murray S, Berenson GS. Influences of FTO gene on onset age of adult overweight. Hum Genet. 2012 Dec;131(12):1851-9. doi: 10.1007/s00439-012-1204-0. Epub 2012 Jul 29.

Mei H, Gu D, Hixson JE, Rice TK, Chen J, Shimmin LC, Schwander K, Kelly TN, Liu DP, Chen S, Huang JF, Jaquish CE, Rao DC, He J. Genome-wide linkage and positional association study of blood pressure response to dietary sodium intervention: the GenSalt Study. Am J Epidemiol. 2012 Oct 1;176 Suppl 7:S81-90. doi: 10.1093/aje/kws290. Epub 2012 Aug 2.

Rebholz CM, Friedman EE, Powers LJ, Arroyave WD, He J, Kelly TN. Dietary protein intake and blood pressure: a meta-analysis of randomized controlled trials. Am J Epidemiol. 2012 Oct 1;176 Suppl 7:S27-43.

Hu T, Mills KT, Yao L, Demanelis K, Eloustaz M, Yancy WS Jr, Kelly TN, He J, Bazzano LA. Effects of low-carbohydrate diets versus low-fat diets on metabolic risk factors: a meta-analysis of randomized controlled clinical trials. Am J Epidemiol. 2012 Oct 1;176 Suppl 7:S44-54.

Kelly TN, Gu D, Rao DC, Chen J, Chen J, Cao J, Li J, Lu F, Ma J, Mu J, Whelton PK, He J. Maternal history of hypertension and blood pressure response to potassium intake: the GenSalt Study. Am J Epidemiol. 2012 Oct 1;176 Suppl 7:S55-63.

Zhao Q, Bazzano LA, Cao J, Li J, Chen J, Huang J, Chen J, Kelly TN, Chen CS, Hu D, Ma J, Rice TK, He J, Gu D. Reproducibility of blood pressure response to the cold pressor test: the GenSalt Study. Am J Epidemiol. 2012 Oct 1;176 Suppl 7:S91-8.

Rebholz CM, Gu D, Chen J, Huang JF, Cao J, Chen JC, Li J, Lu F, Mu J, Ma J, Hu D, Ji X, Bazzano LA, Liu D, He J; GenSalt Collaborative Research Group. Physical activity reduces salt sensitivity of blood pressure: the Genetic Epidemiology Network of Salt Sensitivity Study. Am J Epidemiol. 2012 Oct 1;176 Suppl 7:S106-13.

Krousel-Wood M, He J, Booth M, Chen CS, Rice J, Kahn MJ, Maeshiro R, Whelton PK. Formal public health education and career outcomes of medical school graduates. PLoS One. 2012;7(6):e39020. doi: 10.1371/journal.pone.0039020. Epub 2012 Jun 20.

Rebholz CM, Gu D, Chen J, Huang JF, Cao J, Chen JC, Li J, Lu F, Mu J, Ma J, Hu D, Ji X, Bazzano LA, Liu D, He J; Physical activity reduces salt sensitivity of blood pressure: the genetic epidemiology network of salt sensitivity study. GenSalt Collaborative Research Group. Am J Epidemiol. 2012 Oct 1;176 Suppl 7:S106-13. doi: 10.1093/aje/kws266.

Rebholz CM, Reynolds K, Wofford MR, Chen J, Kelly TN, Mei H, Whelton PK, He J. Effect of soybean protein on novel cardiovascular disease risk factors: a randomized controlled trial. Eur J Clin Nutr. 2012 Nov 28. doi: 10.1038/ejcn.2012.186.

Kelly TN, He J. Gene-sodium interaction and blood pressure: findings from genomics research of blood pressure salt sensitivity. Prog Mol Biol Transl Sci. 2012;108:237-60. Review.

Chen J, Hamm LL, Kleinpeter MA, Husserl F, Khan IE, Chen CS, Liu Y, Mills KT, He C, Rifai N, Simon EE, He J. Elevated plasma levels of endostatin are associated with chronic kidney disease. Am J Nephrol. 2012;35(4):335-40. doi: 10.1159/000336109. Epub 2012 Mar 27.

He J, Reilly M, Yang W, Chen J, Go AS, Lash JP, Rahman M, Defilippi C, Gadegbeku C, Kanthety R, Tao K, Hamm LL, Ojo A, Townsend R, Budoff M; CRIC Investigators. Risk Factors for Coronary Artery Calcium Among Patients With Chronic Kidney Disease (from the Chronic Renal Insufficiency Cohort Study).Am J Cardiol. 2012 Sep 13. pii: S0002-9149(12)01936-4. doi: 10.1016/j. amjcard.2012.07.044.

Chen J, Mohler ER 3rd, Xie D, Shlipak MG, Townsend RR, Appel LJ, Raj DS, Ojo AO, Schreiber MJ, Strauss LF, Zhang X, Wang X, He J, Hamm LL; CRIC Investigators. Risk factors for peripheral arterial disease among patients with chronic kidney disease. Am J Cardiol. 2012 Jul 1;110(1):136-41.

Urinary Albumin: How Low Is Normal? He J, Chen J. J Am Soc Nephrol. 2012 Sep 6.

Zhang Y, Thompson AM, Tong W, Xu T, Chen J, Zhao L, Kelly TN, Chen CS, He J. Biomarkers of inflammation and endothelial dysfunction and risk of hypertension among Inner Mongolians in China. J Hypertens. 2010; 28:35-40.

Gu D, Kelly TN, Hixson JE, Chen J, Liu D, Chen JC, Rao DC, Mu J, Ma J, Jaquish CE, Rice TK, Gu C, Hamm LL, Whelton PK, He J. Genetic variants in the renin-angiotensin-aldosterone system and salt sensitivity of blood pressure. J Hypertens. 2010; 28:1210-20.

Bazzano LA, Gu D, Whelton MR, Wu X, Chen CS, Duan X, Chen J, Chen JC, He J. Body mass index and risk of stroke among Chinese men and women. Ann Neurol. 2010; 67:11-20.

Yang W, Lu J, Weng J, Jia W, Ji L, Xiao J, Shan Z, Liu J, Tian H, Ji Q, Zhu D, Ge J, Lin L, Chen L, Guo X, Zhao Z, Li Q, Zhou Z, Shan G, He J; China National Diabetes and Metabolic Disorders Study Group. Prevalence of diabetes among men and women in China. N Engl J Med. 2010; 362:1090-101.

Kelly TN, Hixson JE, Rao DC, Mei H, Rice TK, Jaquish CE, Shimmin LC, Schwander K, Chen CS, Liu D, Chen J, Bormans C, Shukla P, Farhana N, Stuart C, Whelton PK, He J, Gu D. Genome-wide linkage and positional candidate gene study of blood pressure response to dietary potassium intervention: the genetic epidemiology network of salt sensitivity study. Circ Cardiovasc Genet. 2010; 3:539-47.

Mei H, Chen W, Dellinger A, He J, Wang M, Yau C, Srinivasan SR, Berenson GS. Principal-component-based multivariate regression for genetic association studies of metabolic syndrome components. BMC Genet. 2010; 11:100.

Zheng W, McLerran DF, Rolland B, Zhang X, Inoue M, Matsuo K, He J, Gupta PC, Ramadas K, Tsugane S, Irie F, Tamakoshi A, Gao YT, Wang R, Shu XO, Tsuji I, Kuriyama S, Tanaka H, Satoh H, Chen CJ, Yuan JM, Yoo KY, Ahsan H, Pan WH, Gu D, Pednekar MS, Sauvaget C, Sasazuki S, Sairenchi T, Yang G, Xiang YB, Nagai M, Suzuki T, Nishino Y, You SL, Koh WP, Park SK, Chen Y, Shen C-Y, Thornquist M, Feng Z, Kang D, Boffetta P, Potter JD. Association between body-mass index and risk of death in more than 1 million Asians. N Engl J Med. 2011; 364:719-29.

Paul TK, Chen W, Srinivasan SR, He J, Berenson GS. Contrast of the impact of multiple cardiovascular risk factors on the femoral and carotid intima-media thickness in asymptomatic young adults: The Bogalusa Heart Study. Atherosclerosis. 2011; 216:359-64.

He J, Wofford MR, Reynolds K, Chen J, Chen CS, Myers L, Minor DL, Elmer PJ, Jones DW, Whelton PK. Effect of dietary protein supplementation on blood pressure: a randomized, controlled trial. Circulation. 2011; 124:589-95.

Zhao Q, Gu D, Hixson JE, Liu DP, Rao DC, Jaquish CE, Kelly TN, Lu F, Ma J, Mu J, Shimmin LC, Chen J, Mei H, Hamm LL, He J. Common Variants in Epithelial Sodium Channel Genes Contribute to Salt-Sensitivity of Blood Pressure: The GenSalt Study. Circ Cardiovasc Genet. 2011; 4:375-80.

Thompson AM, Hu T, Eshelbrenner CL, Reynolds K, He J, Bazzano LA. Antihypertensive treatment and secondary prevention of cardiovascular disease events among persons without hypertension: a meta-analysis. JAMA. 2011; 305:913-22.

Kato N, Takeuchi F, Tabara Y, Kelly TN, Go MJ, Sim X, Tay WT, Chen CH, Zhang Y, Yamamoto K, Katsuya T, Yokota M, Kim YJ,  Hee Ong RT, Nabika T, Gu D, Chang LC, Kokubo Y, Huang W, Ohnaka K, Yamori Y, Nakashima E, Jaquish CE, Lee JY, Seielstad M, Isono M, Hixson JE, Chen YT, Miki T, Zhang X, Sugiyama T, Jeon JP, Liu JJ, Takayanagi R, Kim SS, Aung T, Sung YJ, Zhou X, Wong TY, Han BG, Kobayashi S, Ogihara T, Zhu D, Iwai N, Wu JY, Teo YY, Tai ES, Cho YS, He J. Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in East Asians. Nat Genet. 2011; 43:531-8.

He J, Gu D, Kelly TN, Hixson JE, Rao DC, Jaquish CE, Chen J, Zhao Q, Gu C, Huang J, Shimmin LC, Chen JC, Mu J, Ji X, Liu DP, Whelton PK; for the GenSalt Collaborative Research Group. Genetic variants in the renin-angiotensin-aldosterone system and blood pressure responses to potassium intake. J Hypertens. 2011; 29:1719-1730.

Isakova T, Xie H, Yang W, Xie D, Anderson AH, Scialla J, Wahl P, Gutiérrez OM, Steigerwalt S, He J, Schwartz S, Lo J, Ojo A, Sondheimer J, Hsu CY, Lash J, Leonard M, Kusek JW, Feldman HI, Wolf M. Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease. JAMA. 2011;305(23):2432-2439.

Hsu CY, Propert K, Xie D, Hamm L, He J, Miller E, Ojo A, Shlipak M, Teal V, Townsend R, Weir M, Wilson J, Feldman H; CRIC Investigators. Measured GFR does not outperform estimated GFR in predicting CKD-related complications. J Am Soc Nephrol. 2011; 22:1931-7.

Wen W, Cho YS, Zheng W, Dorajoo R, Kato N, Qi L, Chen CH, Delahanty RJ, Okada Y, Tabara Y, Gu D, Zhu D, Haiman CA, Mo Z, Gao YT, Saw SM, Go MJ, Takeuchi F, Chang LC, Kokubo Y, Liang J, Hao M, Le Marchand L, Zhang Y, Hu Y, Wong TY, Long J, Han BG, Kubo M, Yamamoto K, Su MH, Miki T, Henderson BE, Song H, Tan A, He J, Ng DP, Cai Q, Tsunoda T, Tsai FJ, Iwai N, Chen GK, Shi J, Xu J, Sim X, Xiang YB, Maeda S, Ong RT, Li C, Nakamura Y, Aung T, Kamatani N, Liu JJ, Lu W, Yokota M, Seielstad M, Fann CS; Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Wu JY, Lee JY, Hu FB, Tanaka T, Tai ES, Shu XO. Meta-analysis identifies common variants associated with body mass index in east Asians. Nat Genet. 2012; 44:307-11.

Yang W, Xiao J, Yang Z, Ji L, Jia W, Weng J, Lu J, Shan Z, Liu J, Tian H, Ji Q, Zhu D, Ge J, Lin L, Chen L, Guo X, Zhao Z, Li Q, Zhou Z, Shan G, He J; on behalf of the China National Diabetes and Metabolic Disorders Study Investigators. Serum Lipids and Lipoproteins in Chinese Men and Women. Circulation. 2012;125:2212-2221.

Mills KT, Kobori H, Hamm LL, Alper AB, Khan IE, Rahman M, Navar LG, Liu Y, Browne GM, Batuman V, He J, Chen J. Increased urinary excretion of angiotensinogen is associated with risk of chronic kidney disease. Nephrol Dial Transplant. 2012; 27:3176-81.

Chen J, Hamm LL, Kleinpeter MA, Husserl F, Khan IE, Chen CS, Liu Y, Mills KT, He C, Rifai N, Simon EE, He J. Elevated plasma levels of endostatin are associated with chronic kidney disease. Am J Nephrol. 2012; 35:335-40.

Chen J, Mohler ER 3rd, Xie D, Shlipak MG, Townsend RR, Appel LJ, Raj DS, Ojo AO, Schreiber MJ, Strauss LF, Zhang X, Wang X, He J, Hamm LL; CRIC Investigators. Risk Factors for Peripheral Arterial Disease among Patients with Chronic Kidney Disease. Am J Cardiol. 2012; 110:136-41.

Okada Y*, Sim X*, Go MJ*, Wu JY*, Gu D*, Takeuchi F*, Takahashi A, Maeda S, Tsunoda T, Chen P, Lim SC, Wong TY, Liu J, Young TL, Aung T, Seielstad M, Teo YY, Kim YJ, Lee JY, Han BG, Kang D, Chen CH, Tsai FJ, Chang LC, Fann SJ, Mei H, Rao DC, Hixson JE, Chen S, Katsuya T, Isono M, Ogihara T, Chambers JC, Zhang W, Kooner JS; The KidneyGen Consortium; The CKDGen Consortium, Albrecht E; The GUGC consortium, Yamamoto K, Kubo M, Nakamura Y, Kamatani N, Kato N**, He J**, Chen YT**, Cho YS**, Tai ES**, Tanaka T**. Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations (*contributed equally to this work; **jointly directed this work). Nat Genet. 2012; 44:904-909.

Rebholz CM, Friedman EE, Powers LJ, Arroyave WD, He J, Kelly TN. The effect of dietary protein on blood pressure: a meta-analysis of randomized controlled trials. Am J Epidemiol (in press)

Hu T, Mills KT, Demanelis K, Yancy WS, Lu Y, Eloustaz M, Kelly TN, He J, Bazzano L. Effect of low-carbohydrate diets versus low-fat diets on metabolic risk factors: a meta-analysis of randomized controlled clinical trials. Am J Epidemiol (in press)

Kelly TN, Gu D, Jaquish CE, Rao DC, Chen J, Cao J, Chen J, Li J, Lu F, Ma J, Mu J, Whelton PK, He J.  Maternal history of hypertension predicts blood pressure response to potassium intake: The GenSalt Study.  Am J Epidemiol (in press)

Mei H, Gu D, Hixson JE, Rice TK, Chen J, Shimmin LC, Schwander K, Kelly TN, Liu D, Chen S, Huang J, Jaquish CE, Rao DC, He J.  Genome-wide linkage and association study of blood pressure response to dietary sodium intervention: The GenSalt Study.  Am J Epidemiol 2012 Aug 2. [Epub ahead of print]

Gu D, Zhao Q, Kelly TN, Hixson JE, Rao DC, Cao J, Chen J, Li J, Chen J, Ji X, Hu D, Wang X, Liu D, He J. The role of the kallidrein-kinin system genes in the salt-sensitivity of blood pressure: The GenSalt study. Am J Epidemiol (in press)

Zhao Q, Bazzano LA, Cao J, Li J, Chen J, Huang J, Chen J, Kelly TN, Chen CS, Hu D, Ma J, Rice TK, He J, Gu D. Reproducibility of blood pressure response to cold pressor test: the GenSalt study. Am J Epidemiol (in press)

Rebholz CM, Gu D, Chen J, Huang JF, Cao J, Chen JC, Li J, Lu F, Mu J, Ma J, Hu D, Ji X, Bazzano LA, Liu D, He J, the GenSalt Collaborative Research Group. Physical activity decreases salt sensitivity of blood pressure: The GenSalt Study. Am J Epidemiol (in press)

Krousel-Wood M, He J, Booth M, Chen CS, Rice J, Kahn MJ, Maeshiro R, Whelton PK. Formal public health education and career outcomes of medical school graduates. PLoS One. 2012;7(6):e39020.

He J, Reilly M, Yang W, Chen J, Go AS, Lash JP, Rahman M, DeFilippi C, Gadegbeku C, Kanthety R, Tao K, Hamm LL, Ojo A, Townsend R, Budoff M for the CRIC investigators. Risk Factors for Coronary Artery Calcium Among Patients with Chronic Kidney Disease (From theChronic Renal Insufficiency Cohort Study). Am J Cardiol 2012 (in press).

 

Level of Instruction:

graduate

 

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Department of Epidemiology, 1440 Canal Street, Suite 2000, New Orleans, LA 70112, 504-988-6809 tcarter1@tulane.edu