shadow_tr
spacer
people
spacer

 

 Wei Chen    

Wei Chen, MD
Research Professor
Center for Cardiovascular Health
Department of Epidemiology
School of Public Health and Tropical Medicine
Tulane University
1440 Canal Street, Suite 1829
New Orleans, LA 70112
Phone: (504) 988-7611
Fax: (504) 988-7194
wchen1@tulane.edu; wchen1tulane@yahoo.com

 



Research Interests:

Cardiovascular epidemiology; genetic epidemiology; Epidemiological methodology; Metabolic syndrome; Fetal origins of cardiovascular disease  

 

Professional Achievements:

  • 2005 AHA Roger R. Williams Memorial Award for Genetic Epidemiology
  • 2002 AFMR Young Faculty Award, Southern Society for Clinical Investigation
  • 2000 Highest Ranked Research Award, Southern Society for Clinical Investigation
  • 1999 AFMR Young Faculty Award, Southern Society for Clinical Investigation

Educational Background:

  • M.D., Southeast University, Nanjing, China
  • Ph.D., Peking University, Beijing, China

Selected Publications:

Harville EW, Srinivasan S, Chen W, Berenson GS. Is the metabolic syndrome a "small baby" syndrome?: the bogalusa heart study. Metab Syndr Relat Disord. 2012 Dec;10(6):413-21.

Mei H, Chen W, Mills K, He J, Srinivasan SR, Schork N, Murray S, Berenson GS. Influences of FTO gene on onset age of adult overweight. Hum Genet. 2012 Dec;131(12):1851-9.  Epub 2012 Jul 29.

Li S, Chen W, Srinivasan SR, Xu J, Berenson GS. Relation of childhood obesity/cardiometabolic phenotypes to adult cardiometabolic profile: the Bogalusa Heart Study. Am J Epidemiol. 2012 Oct 1;176 Suppl 7:S142-9.

Chen W, Srinivasan SR, Yao L, Li S, Dasmahapatra P, Fernandez C, Xu J, Berenson GS. Low birth weight is associated with higher blood pressure variability from childhood to young adulthood: the Bogalusa Heart Study. Am J Epidemiol. 2012 Oct 1;176 Suppl 7:S99-105.

Nguyen QM, Xu JH, Chen W, Srinivasan SR, Berenson GS. Correlates of age onset of type 2 diabetes among relatively young black and white adults in a community: the Bogalusa Heart Study. Diabetes Care. 2012 Jun;35(6):1341-6. Epub 2012 Mar 7.

Toprak A, Kandavar R, Toprak D, Chen W, Srinivasan S, Xu JH, Anwar A, Berenson GS.C-reactive protein is an independent predictor for carotid artery intima-media thickness progression in asymptomatic younger adults (from the Bogalusa Heart Study). BMC Cardiovasc Disord. 2011 Dec 30;11:78.

Harville EW, Srinivasan S, Chen W, Berenson GS. Is the Metabolic Syndrome a "Small Baby" Syndrome?: The Bogalusa Heart Study. Metab Syndr Relat Disord. 2012 Jul 25.

Mei H, Chen W, Jiang F, He J, Srinivasan S, Smith EN, Schork N, Murray S, Berenson GS. "Longitudinal replication studies of GWAS risk SNPs influencing body mass index over the course of childhood and adulthood". PLoS One. 2012;7(2):e31470. Epub 2012 Feb 15.

Dwyer T, Sun C, Magnussen CG, Raitakari OT, Schork NJ, Venn A, Burns TL, Juonala M, Steinberger J, Sinaiko AR, Prineas RJ, Davis PH, Woo JG, Morrison JA, Daniels SR, Chen W, Srinivasan SR, Viikari JS, Berenson GS. Cohort Profile: The International Childhood Cardiovascular Cohort (i3C) Consortium. Int J Epidemiol. 2012 Mar 20. [Epub ahead of print].

Berenson GS, Chen W, Hassig S, Nguyen QM, Rice J, Srinivasan SR, Xu JH. Elevated liver function enzymes are related to the development of prediabetes and type 2 diabetes in younger adults: the Bogalusa Heart Study. Diabetes Care. 2011 Dec;34(12):2603-7. [Epub 2011 Sep 27].

Kelly RE, Dasmahapatra P, Wang J, Chen W, Srinivasan SR, Fernandez C, Xu J, Martin-Schild S, Berenson GS. Prevalence of atherosclerotic plaque in young and middle-aged asymptomatic individuals: the Bogalusa heart study. South Med J. 2011 Dec; 104(12):803-8

Oikonen M, Tikkanen E, Juhola J, Tuovinen T, Seppala I, Juonala M, Taittonen L, Mikkila V, Kahonen M, Ripatti S, Viikari J, Lehtimaki T, Havulinna AS, Kee F, Newton-Cheh C, Peltonen L, Schork NJ, Murray SS, Berenson GS, Chen W, Srinivasan SR, Salomma V, Raitakari OT. Genetic Variants and Blood Pressure in a Population-Based Cohort: The Cardiovascular Risk in Young Finns Study. Hypertension. 2011 Oct 24. [Epub ahead of print]

Berenson GS, Chen W, Dasmahapatra P, Fernandez C, Giles T, Xu J, Srinivasan SR.  Stimulus response of blood pressure in black and white young individuals helps explain racial divergence in adult cardiovascular disease: the Bogalusa Heart Study. Journal of the American Society of Hypertension. 2011 Jul-Aug;5(4):230-8. Epub 2011 Apr 13.

Bazzano LA, Belame SN, Patel DA, Chen W, Srinivasan S, McIlwain E, Berenson GS. Obesity and left ventricular dilatation in young adulthood: the bogalusa heart study. Clin Cardiol. 2011 Mar;34(3):153-9. doi: 10.1002/clc.20896.

Berenson GS, Agirbasli M, Nguyen QM, Chen W, Srinivasan SR. Glycemic status, metabolic syndrome, and cardiovascular risk in children. Med Clin North Am. 2011 Mar;95(2):409-17.

Chen W, Kimura M, Cao X, Srinivasan SR, Berenson GS, Kark JD, Aviv A. Longitudinal and Cross-Sectional Evaluations of Leukocyte Telomere Length Dynamics: Age-Dependent LTL Shortening is the Rule. J Gerontol Med Sci (in press).

Paul TK, Chen W, Srinivasan SR, He J, Berenson GS. Contrast of the impact of multiple cardiovascular risk factors on the femoral and carotid intima-media thickness in asymptomatic young adults: The Bogalusa Heart Study. Atherosclerosis. 2011 Jun:216(2):359-64. Epub 2011 Feb 18.

Chen W, Srinivasan SR, Ruan L, Mei H, Berenson GS. Adult Hypertension Is Associated With Blood Pressure Variability in Childhood in Blacks and Whites: The Bogalusa Heart Study. Am J Hypertens 2011;24(1):77-82, PMID: 20725054.  

Chen W, Srinivasan SR, Berenson GS. Amplification of the Association between Birthweight and Blood Pressure with Age: The Bogalusa Heart Study. J Hypertens 2010;28(10):2046-2052, PMID: 20616754.  

Chen W, Srinivasan SR, Xu J, Berenson GS. Black-White Divergence in the Relation of White Blood Cell Count to Aspects of Metabolic Syndrome in Preadolescents, Adolescents and Young Adults: The Bogalusa Heart Study. Diabetes Care 2010;33(11):2474-6, PMID: 20798336.  

Chen W, Srinivasan SR, Hallman DM, Berenson GS. The relationship between birth weight and longitudinal changes of blood pressure is modulated by beta-adrenergic receptor genes: The Bogalusa Heart Study. J Biomed Biotechnol 2010;2010:543514, PMID: 20467565.  

Levy D, Neuhausen SL*, Hunt SC*, Kimura M*, Hwang SJ*,  Chen W*, Bis J*, Fitzpatrick A*, Smith S, Johnson AD, Gardner JP, Srinivasan SR, Schork N, Rotter J,  Herbig U, Psaty B, Sastrasinh M, Murray SS, Vasan R, Province MG, Glazer N, Lu X, Cao X, Kronmal R, Berenson GS, Aviv A. Genome-wide Association Identifies OBFC1 as a Locus Involved in Human Leukocyte Telomere Biology. Proc Natl Acad Sci USA 2010;107(20):9293-8, PMID: 20421499  * equally contributed.  

Chen W, Gardner JP, Kimura M, Brimacombe M, Cao X, Srinivasan SR, Berenson GS, Aviv A. Leukocyte telomere length is associated with HDL cholesterol levels: The Bogalusa heart study. Atherosclerosis 2009;205(2):620-625, PMID: 19230891.  

Chen W, Srinivasan SR, Berenson GS. Influence of birth weight on white blood cell count in biracial (black-white) children, adolescents, and young adults: the Bogalusa Heart Study. Am J Epidemiol 2009;169(2):214-218, PMID: 19064646.  

Chen W, Srinivasan SR, Xu J, Berenson GS. Effect of parental coronary artery disease on adverse effects of the metabolic syndrome and aging on carotid artery intima-media thickness (from the Bogalusa Heart Study). Am J Cardiol 2008;102(2):180-183, PMID: 18602517.  

Chen W, Srinivasan SR, Berenson GS. Path analysis of metabolic syndrome components in black versus white children, adolescents, and adults: the Bogalusa Heart Study. Ann Epidemiol 2008;18(2):85-91, PMID: 18191760.  

Chen W, Srinivasan SR, Berenson GS. Differential Effect of Heart Rate on Arterial Wall Stiffness and Thickness in Younger Adults: The Bogalusa Heart Study. J Clin Hypertens 2008;2:152-157.  

Lanktree MB, … …, Chen W, et al. Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet 2011;88(1):6-18, PMID: 21194676.  

Elks CE, … …, Chen W, et al. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet 2010 Nov 21. [Epub ahead of print] PMID: 21102462.  

Wang J, Chen W, Ruan L, Toprak A, Srinivasan SR, Berenson GS. Differential Impact of Elevated Blood Pressure on Left Ventricular Geometry Types in Black and White Young Adults in a Community (from the Bogalusa Heart Study). Am J Cardiol (in press).  

Nguyen QM, Toprak A, Xu JH, Srinivasan SR, Chen W, Berenson GS. Progression of Segment-Specific Carotid Artery Intima-Media Thickness in Young Adults (from the Bogalusa Heart Study). Am J Cardiol 2011;107(1):114-9, PMID:21146698.  

Camhi SM, Katzmarzyk PT, Broyles ST, Srinivasan SR, Chen W, Bouchard C, Berenson GS. Subclinical Atherosclerosis and Metabolic Risk: Role of Body Mass Index and Waist Circumference. Metab Syndr Relat Disord. 2010 Dec 6 [Epub ahead of print], PMID: 21133775.  

Berenson GS, Srinivasan SR, Fernandez C, Chen W, Xu J. Can adult cardiologists play a role in the prevention of heart disease beginning in childhood? Methodist Debakey Cardiovasc J 2010;6(4):4-9, PMID: 21088652.  

Mei H, Chen W, Dellinger A, He J, Wang M, Yau C, Srinivasan SR, Berenson GS. Principal-component-based multivariate regression for genetic association studies of metabolic syndrome components. BMC Genet 2010;11:100, PMID: 21062472.  

Paul TK, Chen W, Srinivasan SR, Rice J, Toprak A, He J, Berenson GS. Framingham risk score is associated with femoral artery intima-media thickness in asymptomatic young adults (the Bogalusa heart study). Atherosclerosis 2010;213(2):627-31, PMID: 20970137.  

Magnussen CG, Koskinen J, Chen W, Thomson R, Schmidt MD, Srinivasan SR, Kivimäki M, Mattsson N, Kähönen M, Laitinen T, Taittonen L, Rönnemaa T, Viikari JS, Berenson GS, Juonala M, Raitakari OT. Pediatric metabolic syndrome predicts adulthood metabolic syndrome, subclinical atherosclerosis, and type 2 diabetes mellitus but is no better than body mass index alone: the Bogalusa Heart Study and the Cardiovascular Risk in Young Finns Study. Circulation 2010;122(16):1604-1611, PMID: 20921439.  

Mokha JS, Srinivasan SS, Dasmahapatra P, Fernandez C, Chen W, Xu J, Berenson GS. Utility of waist-to-height ratio in assessing the status of central obesity and related cardiometabolic risk profile among normal weight and overweight/ obese children: The Bogalusa Heart Study. BMC Pediatr 2010;10(1):73.  

Juonala M, Magnussen CG, Venn A, Dwyer T, Burns TL, Davis PH, Chen W, Srinivasan SR, Daniels SR, Kähönen M, Laitinen T, Taittonen L, Berenson GS, Viikari JS, Raitakari OT. Influence of Age on Associations Between Childhood Risk Factors and Carotid Intima-Media Thickness in Adulthood: The Cardiovascular Risk in Young Finns Study, the Childhood Determinants of Adult Health Study, the Bogalusa Heart Study, and the Muscatine Study for the International Childhood Cardiovascular Cohort (i3C) Consortium. Circulation 2010;122(24):2514-20, PMID: 21126976.  

Smith EN, Shaw M, Salem R, Chen W, Srinivasan SR, Topol EJ, Schork NJ, Berenson GS, Murray SS. Longitudinal Genome-Wide Association of Cardiovascular Disease Risk Factors in The Bogalusa Heart Study. PLoS Genet 2010 Sep 9;6(9). pii:e1001094,PMID: 20838585.  

Mei H, Chen W, Srinivasan SR, Jiang F, Schork N, Murray S, Smith E, So JD, Berenson GS. FTO influences on longitudinal BMI over childhood and adulthood and modulation on relationship between birth weight and longitudinal BMI. Hum Genet 2010;128(6):589-96, PMID: 20811910.  

Ruan L, Chen W, Srinivasan SR, Xu J, Toprak A, Berenson GS. Relations of Serum Phosphorus Levels to Carotid Intima-media Thickness in Asymptomatic Young Adults (from the Bogalusa Heart Study). Am J Cardiol 2010;106(6):793-7, PMID: 20816119.  

Broyles S, Katzmarzyk PT, Srinivasan SR, Chen W, Bouchard C, Freedman DS, Berenson GS.The Pediatric Obesity Epidemic Continues Unabated in Bogalusa, Louisiana. Pediatrics 2010;125(5):900-5, PMID: 20368311.  

Toprak D, Toprak A, Chen W, Xu JH, Srinivasan S, Berenson GS.Adiposity in Childhood Is Related to C-Reactive Protein and Adiponectin in Young Adulthood: From the Bogalusa Heart Study. Obesity (Silver Spring) 2011;19(1):185-90, PMID: 20360758.  

Paul TK, Chen W, Srinivasan SR, Toprak A, He J, Berenson GS. Gender Divergence on the Impact of Multiple Cardiovascular Risk Factors on the Femoral Artery Intima-Media Thickness in Asymptomatic Young Adults: The Bogalusa Heart Study. American Journal of the Medical Sciences, 2012 Jan; 343(1):40-5

Camhi SM, Katzmarzyk PT, Broyles S, Srinivasan SR, Chen W, Bouchard C, Berenson GS. Predicting Adult Body Mass Index-Specific Metabolic Risk From Childhood. Metab Syndr Relat Disord 2010;8(2):165-172, PMID: 20156071.  

Nguyen QM, Srinivasan SR, Xu JH, Chen W, Berenson GS. Fasting plasma glucose levels within the normoglycemic range in childhood as a predictor of prediabetes and type 2 diabetes in adulthood: the Bogalusa Heart Study. Arch Pediatr Adolesc Med 2010;164(2):124-128, PMID: 20124140.  

Nguyen QM, Srinivasan SR, Xu JH, Chen W, Kieltyka L, Berenson GS. Utility of childhood glucose homeostasis variables in predicting adult diabetes and related cardiometabolic risk factors: the Bogalusa Heart Study. Diabetes Care 2010;33(3):670-675, PMID: 20009096.  

Nguyen QM, Srinivasan SR, Xu JH, Chen W, Berenson GS. Distribution and cardiovascular risk correlates of plasma soluble intercellular adhesion molecule-1 levels in asymptomatic young adults from a biracial community: the Bogalusa Heart Study. Ann Epidemiol 2010;20(1):53-9, PMID: 20006276.  

Bhuiyan AR, Chen W, Srinivasan SR, Azevedo MJ, Berenson GS. Relationship of Low Birth Weight to Pulsatile Arterial Function in Asymptomatic Younger Adults: The Bogalusa Heart Study. Am J Hypertens 2010;23:168-173, PMID: 19942864.  

Kabir AA, Srinivasan SR, Sultana A, Chen W, Wei CY, Berenson GS. Association between depression and intima-media thickness of carotid bulb in asymptomatic young adults. Am J Med 2009;122(12):1151.e1-8, PMID: 19958896.  

Muntner P, Arshad A, Morse SA, Patel DA, Manapatra PD, Reisin E, Aguilar EA, Chen W, Srinivasan S, Berenson GS. End-stage renal disease in young black males in a black-white population: longitudinal analysis of the Bogalusa Heart Study. BMC Nephrol 2009;10:40, PMID: 19954521.  

Srinivasan SR, Wang R, Chen W, Wei CY, Xu J, Berenson GS. Utility of waist-to-height ratio in detecting central obesity and related adverse cardiovascular risk profile among normal weight younger adults (from the Bogalusa Heart Study). Am J Cardiol 2009;104(5):721-724,  

Nguyen QM, Srinivasan SR, Xu JH, Chen W, Berenson GS. Influence of childhood parental history of type 2 diabetes on the pre-diabetic and diabetic status in adulthood: the Bogalusa Heart Study. Eur J Epidemiol 2009;24(9):537-9, PMID: 19618280.  

Patel DA, Srinivasan SR, Chen W, Berenson GS. Influence of the metabolic syndrome versus the sum of its individual components on left ventricular geometry in young adults (from the Bogalusa Heart Study). Am J Cardiol 2009;104(1):69-73, PMID: 19576323.  

Ruan L, Chen W, Srinivasan SR, Xu J, Toprak A, Berenson GS. Plasma homocysteine is adversely associated with glomerular filtration rate in asymptomatic black and white young adults: the Bogalusa heart study. Eur J Epidemiol 2009;24(6):315-9, PMID: 19396552.  

Mzayek F, Sherwin R, Hughes J, Hassig S, Srinivasan S, Chen W, Berenson GS. The Association of Birth Weight with Arterial Stiffness at Mid-Adulthood: The Bogalusa Heart Study. J Epidemiol Community Health 2009;63:729-733, PMID: 19429574.  

Sisson SB, Katzmarzyk PT, Srinivasan SR, Chen W, Freedman DS, Bouchard C, Berenson GS. Ethnic Differences in Subcutaneous Adiposity and Waist Girth in Children and Adolescents. Obesity (Silver Spring) 2009;17(11):2075-81, PMID: 19390519.  

Ruan L, Chen W, Srinivasan SR, Xu J, Sun M, Toprak A, Berenson GS. Relation of plasma homocysteine to arterial stiffness in black and white young adults (from the Bogalusa Heart Study). Am J Cardiol 2009;103(7):985-8, PMID: 19327427.  

Toprak A, Reddy J, Chen W, Srinivasan S, Berenson G. Relation of pulse pressure and arterial stiffness to concentric left ventricular hypertrophy in young men (from the Bogalusa Heart Study). Am J Cardiol 2009;103(7):978-84, PMID: 19327426.  

Toprak A, Wang H, Chen W, Paul T, Ruan L, Srinivasan S, Berenson G. Prehypertension and black-white contrasts in cardiovascular risk in young adults: Bogalusa Heart Study. J Hypertens 2009;27(2):243-50, PMID: 19226697.  

Ruan L, Chen W, Srinivasan SR, Sun M, Wang H, Toprak A, Berenson GS. Correlates of common carotid artery lumen diameter in black and white younger adults: the Bogalusa Heart Study. Stroke 2009;40(3):702-7, PMID: 19131651.  

Aviv A, Chen W, Gardner JP, Kimura M, Brimacombe M, Cao X, Srinivasan SR, Berenson GS. Leukocyte telomere dynamics: longitudinal findings among young adults in the Bogalusa Heart Study. Am J Epidemiol 2009;169(3):323-9, PMID: 19056834.  

Nguyen QM, Srinivasan SR, Xu JH, Chen W, Berenson GS. Distribution and cardiovascular risk correlates of hemoglobin A(1c) in nondiabetic younger adults: the Bogalusa Heart Study. Metabolism 2008;57(11):1487-92, PMID: 18940383.  

Nguyen QM, Srinivasan SR, Xu JH, Chen W, Berenson GS. Changes in risk variables of metabolic syndrome since childhood in pre-diabetic and type 2 diabetic subjects: the Bogalusa Heart Study. Diabetes Care 2008;31(10):2044-9, PMID: 18628566  

Bhuiyan AR, Chen W, Srinivasan SR, Rice JC, Mock NB, Tang R, Gene Bond M, Boerwinkle E, Berenson GS. Interaction of G-protein beta3 subunit and nitric oxide synthase gene polymorphisms on carotid artery intima-media thickness in young adults: the Bogalusa Heart Study. Am J Hypertens 2008;21(8):917-21, PMID: 18551105  

Berenson GS, Patel DA, Srinivasan SR, Chen W. Pressure-heart rate product changes from childhood to adulthood in a biracial population - A crossover phenomenon: The Bogalusa Heart Study. J Clin Hypertens 2008;2:80-87.  

Toprak A, Wang H, Chen W, Paul T, Srinivasan SR, Berenson GS. Relation of childhood risk factors to left ventricular hypertrophy (eccentric or concentric) in relatively young adulthood (from the Bogalusa Heart Study). Am J Cardiol 2008;101(11):1621-1625, PMID: 18489940  

Muntner P, Srinivasan SR, Menke A, Patel DA, Chen W, Berenson GS. Impact of childhood metabolic syndrome components on the risk of elevated uric acid in adulthood: the Bogalusa Heart Study. Am J Med Sci 2008;335(5):332-7, PMID: 18480647  

Hunt SC, Chen W, Gardner JP, Kimura M, Srinivasan SR, Eckfeldt JH, Berenson GS, Aviv A. Leukocyte telomeres are longer in African Americans than in whites: the National Heart, Lung, and Blood Institute Family Heart Study and the Bogalusa Heart Study. Aging Cell 2008;7(4):451-8, PMID: 18462274  

Bhuiyan AR, Srinivasan SR, Chen W, Sultana A, Berenson GS. Association of serum bilirubin with pulsatile arterial function in asymptomatic young adults: the Bogalusa Heart Study. Metabolism 2008;57(5):612-6, PMID: 18442622  

Nguyen QM, Srinivasan SR, Xu JH, Chen W, Berenson GS. Racial (black-white) divergence in the association between adiponectin and arterial stiffness in asymptomatic young adults: the Bogalusa heart study. Am J Hypertens 2008;21(5):553-7, PMID: 18292758  

Freedman DS, Patel DA, Srinivasan SR, Chen W, Tang R, Bond MG, Berenson GS. The contribution of childhood obesity to adult carotid intima-media thickness: the Bogalusa Heart Study. Int J Obes (Lond) 2008;32(5):749-56, PMID: 18227845

 

Level of Instruction:

graduate

 

[ View all Epidemiology Faculty ]

 

 
spacer

Department of Epidemiology, 1440 Canal Street, Suite 2000, New Orleans, LA 70112, 504-988-6809 tcarter1@tulane.edu