Lei Zhang
Postdoctoral Fellow
Department of Biostatistics and Bioinformatics
Tulane University School of Public Health and Tropical Medicine
1440 Canal Street, Suite 2005
New Orleans, LA 70112
Tel: (504) 988-2029
Fax: (504) 988-1706


Research Interests:

My major research interest is applied statistics in genetics. Basically, we apply the existing statistical methods as well as develop new methods to study and identify genetic components for complex traits/diseases including osteoporosis, bone mineral density, fracture, and others. My current focus includes efficient rare variants-aimed genome-wide association studies based on next-generation sequencing and imputation datasets, for bone mineral density and related traits.



  • Ph.D., Center for Molecular genetics, Xi'an jiaotong university, China, 2005
  • B.S., Bioengineering Department, Xi'an jiaotong university, China, 2001

Major Publications:

Liu YJ, Zhang L, Pei Y, Papasian CJ, Deng HW. On Genome-Wide Association Studies and Their Meta-Analyses: Lessons Learned From Osteoporosis Studies. J Clin Endocrinol Metab. 2013 Jun 19.

Zhang L, Pei YF, Hai R, Lin Y, Deng HW. Testing Rare Variants for Association with Disease: A Bayesian Marker Selection Approach. Ann Hum Genet. 2012 Jan;76(1):74-85.

Zhang L, Pei YF, Li J, Papasian CJ, Deng HW. Efficient Utilization of Rare Variants for Detection of Disease-Related Genomic Regions. PLoS One. 2010 Dec 10; 5(12): e14288.

Zhang L, Pei YF, Li J, Papasian CJ, Deng HW. Improved Detection of Rare Genetic Variants for Diseases. PLoS One 2010 Nov 8: e13857.

Zhang L, Liu J, Deng HW. A Multilocus Linkage Disequilibrium Measure Based on Mutual Information Theory and Its Applications. Genetica. 2009 Dec;137(3):355-64.

Zhang L, Bonham AJ, Li J, Pei YF, Chen J, Papasian CJ, Deng HW. Family Based Bivariate Association Tests for Quantitative Traits. PLoS One. 2009 Dec 2; 4(12):e8133.

Zhang L, Li J, Pei YF, Liu YJ, Deng HW. Tests of Association for Quantitative Traits in Nuclear Families Using Principal Components to Correct for Population Stratification. Annals of Human Genetics. 2009 Nov;73(Pt 6):601-13.

Zhang L, Pei YF, Li J, Papasian CJ, Deng HW. Univariate/Multivariate Genome-Wide Association Scans Using Data from Families and Unrelated Samples. PLoS One. 2009 Aug 4; 4(8): e6502.





Department of Biostatistics, 1440 Canal Street, Suite 2001, New Orleans, LA 70112, 504-988-5164