Department of Biostatistics and Bioinformatics
Tulane University School of Public Health and Tropical Medicine
1440 Canal Street, Suite 2001
New Orleans, LA 70112
Tel: (504) 988-2035
Fax: (504) 988-1706
I have several years' experience working in statistical modeling of genetic problems and analyzing experimental data to identify genetic component for complex diseases. Currently, I'm mainly focusing on methodology development and investigation in genetic association studies and data analysis for genome-wide association studies.
- Ph. D. in Biochemistry and Molecular Biology, Xi'an Jiaotong University, 2010
- B.S. in Mathematics & Applied Mathematics, Xi'an Jiaotong University, 2005
Honors or Awards:
- The 14th Summer Institute in Statistical Genetics Award. University of Washington, 2009.
Liu YJ, Zhang L, Pei Y, Papasian CJ, Deng HW. On Genome-Wide Association Studies and Their Meta-Analyses: Lessons Learned From Osteoporosis Studies. J Clin Endocrinol Metab. 2013 Jun 19.
Chen J, Zhang JG, Li J, Pei YF, Deng HW. On combining reference data to improve imputation accuracy. PLoS One. 2013;8(1):e55600.
Pei YF, Zhang L, Liu J, Deng HW. Multivariate association test using haplotype trend regression. Ann Hum Genet. 2009 Jul;73(Pt 4): 456-64.
Pei YF, Li J, Zhang L, Papasian CJ, Deng HW. Analyses and comparison of accuracy of different genotype imputation methods. PLoS One. 2008;3(10):e3551.
Pei YF, Zhang L, Deng HW, Dvornyk V. CYP17 MspA1 polymorphism and age at menarche: a meta-analysis. Dis Markers. 2008;25(2):87-95.
Pei YF, Zhang L, Li J, Deng HW. Analyses and Comparison of imputation-based association methods. 2010 May 26;5(5):e10827.
Pei YF, Zhang L, Yang -L, Han Y, Hai R, Ran S, Tian Q, Shen H, Li J, Zhu XZ, Luo X, Deng HW. Genome-Wide Association Study of Copy Number Variants Suggests LTBP1 and FGD4 Are Important for Alcohol Drinking. PLoS ONE 2012;7(1): e30860.
Liu YZ, Pei YF, Guo YF, Wang L, Liu XG, Yan H, Xiong DH, Zhang YP, Levy S, Li J, Haddock CK, Papasian CJ, Xu Q, Ma JZ, Payne TJ, Recker RR, Li MD, Deng HW. Genome-wide association analyses suggested a novel mechanism for smoking behavior regulated by IL15. Molecular Psychiatry 2009; 14: 668–680.
Liu YZ, Pei YF, Liu JF, Yang F, Guo Y, Zhang L, Liu XG, Yan H, Wang L, Zhang YP, Levy S, Recker RR, Deng HW. Powerful bivariate genome-wide association analyses suggest the SOX6 gene influencing both obesity and osteoporosis phenotypes in males. PloS One. 2009 Aug 28; 4(8):e6827.
Liu J, Pei YF, Papasian CJ, Deng HW. Bivariate association analyses for the mixture of continuous and binary traits with the use of extended generalized estimating equations. Genet Epidemiol. 2009 Apr;33(3):217-27.
Zhang L, Pei YF, Li J, Papasian CJ, Deng HW. Univariate/multivariate genome-wide association scans using data from families and unrelated samples. PLoS One. 2009 4(8):e6502.
Deng FY, Zhao LJ, Pei YF, Sha BY, Liu XG, Yan H, Wang L, Yang TL, Recker RR, Papasian CJ, Deng HW. Genome-wide copy number variation association study suggested VPS13B gene for osteoporosis in Caucasians. Osteoporosis Int. 2010 21(4): 579-87.
Zhang L, Li J, Pei YF, Liu Y, Deng HW. Tests of association for quantitative traits in unclear fanilies using principal components to correct for population stratification. Ann Hum Genet. 2009 Nov;73(Pt 6):601-13.
Guo Y, Zhang LS, Yang TL, Tian Q, Xiong DH, Pei YF, Deng HW. PTH and IL21R May Underlie Variation of Femoral Neck Bone Mineral Density as Revealed by a Genome-Wide Association Study. J Bone Miner Res. 2010 25(5):1042-48.
Liu YZ, Guo YF, Wang L, Tan LJ, Liu XG, Pei YF, Yan H, Xiong DH, Deng FY, Yu N, Zhang YP, Zhang L, Lei SF, Chen XD, Liu HB, Zhu XZ, Levy S, Papasian CJ, Drees BM, Hamilton JJ, Recker RR, Deng HW.Genome-wide association analyses identify SPOCK as a key novel gene underlying age at menarche.PLoS Genet. 2009 Mar;5(3).
DE Moor MH, Liu YJ, Boomsma DI, Li J, Hamilton JJ, Hottenga JJ, Levy S, Liu XG, Pei YF, Posthuma D, Recker RR, Sullivan PF, Wang L, Willemsen G, Yan H, DE Geus EJ, Deng HW. Genome-Wide Association Study of Exercise Behavior in Dutch and American Adults. Med Sci Sports Exerc. 2009 Sep 2.
Liu YJ, Guo YF, Zhang LS, Pei YF, Yu N, Yu P, Papasian CJ, Deng HW. Biological pathway-based genome-wide association analysis identified the vasoactive intestinal peptide (VIP) pathway important for obesity. Obesity (Silver Spring). 2010 Apr 8.
Zhang L, Pei YF, Hai R, Lin Y, Deng HW. Testing Rare Variants for Association with Diseases: a Bayesian Marker Selection Approach. Annals of Human Genetics. 2012;76(1):74-85.