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 Sudesh Srivastav    

Sudesh Srivastav, PhD
Professor
Department of Biostatistics & Bioinformatics
Tulane University School of Public Health and Tropical Medicine
1440 Canal St, Room 2019
New Orleans, LA 70112
Phone: 504.504.988.2472
Fax: (504) 988-1706
ssrivas@tulane.edu

 



Research Interests:

Microarray data, experimental designs, crossover designs, diallel cross designs, biological sequence alignment and genome analysis, statistical methods in genetics, design and analysis of clinical trials, multicenter clinical trials.


Professional Achievements:

 

  • 2009 Recipient, Undergraduate Public Health Studies Research and Teaching Award Grant, Tulane                             University Health Sciences Center, New Orleans, USA
  • 2005  Recipient, Award for Excellence in Intercampus Collaborative Research, Tulane University Health Sciences Center, New Orleans, USA.
  • 2005 LCRC Supported Travel Money for Courses in Practical DNA Microarray Analysis,
  • 2003 NSF Supported Travel Grant for Conference on New Directions in Experimental Design, Chicago, Illinois, USA.
  • 2002 NSF Travel Award for Conference on Designs for Generalized Linear Models, National Institute of Standard and Technology, Gaithersburg, Maryland, USA.
  • 2002 Honorary Member, Delta Omega Society in Public Health, Eta Chapter, Tulane University School of Public Health and Tropical Medicine.

Educational Background:

  • PhD, statistics, Old Dominion University 1996
  • MS, applied mathematics, New Jersey Institute of Technology
  • MSTAT, statistics, Indian Statistical Institute, India, 1988

Selected Publications:

Wysocki JD, Srivastav S, Winstead NS. A nationwide analysis of risk factors for mortality and time to endoscopy in upper gastrointestinal haemorrhage. Aliment Pharmacol Ther. 2012 Jul;36(1):30-6. doi: 10.1111/j.1365-2036.2012.05129.x.

Morgan, JP & Srivastav, SK (2000). On the Type-1 optimality of Nearly Balanced Incomplete Block Designs with small Concurrence range, Statistica Sinica, Vol. 10, issue 4, 1091-1116.

Prevrhal S, Fuerst T, Fan B, Njeh CF, Hans D, Uffmann M, Srivastav SK, Genant HK (2001). What Does Quantitative Ultrasound of the Tibia Measure? Osteoporosis International, Vol. 12, issue no. 1, 20-26.

Bonel HM, Schneider P, Seemann MD, Hugli R, Srivastav SK, Lodemann KP, Reiser M (2001). MR imaging of the wrist in rheumatoid arthritis using gadobenate dimeglumine, Skeletal Radiology, Vol. 30, 15-24.

Ruiz-Deya, G, Davis R, Srivastav SK, Nguyen, A, & Thomas R (2001). Outpatient Radical Prostatectomy: Impact of Standardized Perineal Approach on Patients Outcomes, The Journal of Urology, volume 166, 581-586.

Bonel HM, Heuck A, Frei KA, Herrmann K, Scheidler J, Srivastav SK, Reiser M (2001). Carpal Tunnel Syndrome: Assessment by Turbo Spin Echo, Spin Echo, and Magnetization Transfer Imaging Applied in a Low-Field MR System, Journal of Computer Assisted Tomography, Vol 25 issue no. 1, 137-145.

Srivastav, SK & Morgan, JP (2001). Constructions for generalized group divisible designs in setting admitting symmetry, American Journal of Mathematical and Management Sciences, Vol. 2, NOS. 1 & 2, 69-89.

Eroglu, GE, Rabito FA, Srivastav, SK (2002). Mortality From Asthma in Children and Young Adults in Louisiana, Annals of Allergy, Asthma and Immunology, Vol. 89, 191-194.

Srivastav, SK & Morgan, JP (2002). On E-optimality of Truncated Block Designs, Metrika, Vol. 56: 239-245.

Morgan, JP & Srivastav, SK (2002). The Completely Symmetric Designs Blocksize Three, Journal of Statistical Planning and Inference, vol.106, 21-30.

Srivastav, SK (2002).  On construction of generalized group divisible designs with two groups, Communications in Statistics - Theory and Methods, Vol. 31 issue no. 4, 639-647.

Srivastav, SK & Shankar A (2003). On the E-optimality of certain class of block designs, Statistics and Probability letters, vol. 65, 187-193.

IS Fortgang, SK Srivastav, GB Baskin, PM Schumacher, and LS Levy (2003). Retrospective Analysis of Clinical and Laboratory Factors Associated with Lymphoma in Simian AIDS, Leukemia and Lymphom, vol. 45: 161-169.  

Rempala, GA & Srivastav, SK (2004). Minimum Variance Rectangular Designs for U-statistics, Journal of Statistical Planning and Inference, vol. 120 Issue 1-2, 103-118.

Daldrup-Link HE, Okuhata Y, Wolfe A, Srivastav SK, Oie S, Ferrara N, Cohen RL, Shames DM, Brasch R [2004]. Decrease in tumor apparent permeability-surface area product to a MRI macromolecular contrast medium following angiogenesis inhibition with correlations to cytotoxic drug accumulation. Microcirculation 2004; 11:387-396.

Jager L, Bonell H, Liebl M, Srivastav SK, Arbusov V, Hempel M, Reiser M (2005). Multi-Slice-Ct Anatomy of the Normal Temporal Bone: A Comparison to Single-Slice-Ct. Radiology, vol. 235, 133-141.

Srivastav, SK  & Shankar A. (2005). Some methods of constructing generalized group divisible designs with two groups Communications in Statistics - Theory and Methods, vol. 34, Issue 1: 127-136.

Bonel HM, Jager L, Frei KA, Galiano S, Srivastav SK, Flohr T, Reiser M, Dinkel HP (2005). Optimization of multidetector computed tomography of the wrist to achieve diagnostic image quality with minimum radiation exposure, American Journal of  Roentgenology, vol. 185:647-654.

Srivastav SK & Shankar A. (2005). Resolvable balanced incomplete block designs with m-identical resolvable classes (RBIBD(m), Journal of Combinatorics, Information & System Science (JCISS), vol. 29, Nos. 1-4, 143-149.

Fatih Atug, Erik P. Castle, Sudesh K Srivastav Scott V Burgess, Raju Thomas, and Rodney Davis (2006). Prospective evaluation of performing concomitant lymphadenectomy in robotic-assisted radical prostatectomy; preliminary analysis of outcomes. Journal of Endourology, vol. 20(7):514-518.

Mather FJ, Chen VW, Morgan LH, Correa CN, Shaffer JG, Srivastav SK, Rice JC, Blount G, Swalm CM, Wu X, Scribner RA (2006). Hierarchical Modeling and Other Spatial Analyses in Prostate Cancer Incidence Data. American Journal of Preventive Medicine, Vol. 30, No 2, Supplement 1, S88 – S100.

Fatih Atug, Erik P. Castle, Sudesh K Srivastav, Scott V Burgess, Raju Thomas, and Rodney Davis (2006). Positive Surgical Margins in Robotic-Assisted Radical Prostatectomy: Impact of Learning Curve on Oncologic Outcomes, European Urology, vol. 49(5):866-872.

Salvo, V.,A., Boue, S.M., Fonseca J.P., Elliott, S., Corbitt, C., Collins-Burow, B.M.,  Curiel, T.J., Srivastav, S.K., Shih, B.Y., Carter-Wientjes, C., Wood, C.E., Erhardt, P., Beckman, B.S., McLachlan, J.A., Cleveland, T.E., Burow, M.E. Antiestrogenic Glyceollins Suppress Human Breast and Ovarian Carcinoma Tumorigenesis. Clinical Cancer Research 12(23): 7159-7164 (2006).

Erik P. Castle, Fatih Atug, Michael Woods, Sudesh K Srivastav, Raju Thomas, and Rodney Davis (2006). Impact of Body Mass Index on Perioperative Morbidity after Robotic Assisted Radical Prostatectomy, Associazione onlus per la Cura delle Patologie Uro-Andrologiche, Bologna, MP26-29.

Fatih Atug, Erik P. Castle, Sudesh K Srivastav, Scott V Burgess, Raju Thomas, and Rodney Davis (2006). Positive Surgical Margins in Robotic-Assisted Radical Prostatectomy: Impact of Learning Curve on Oncologic Outcomes, European Urology, vol. 49(5):866-872.

Di Zhao, Elangovan Vellaichamy, Naveen K Somanna, and Kailash N. Pandey (2007). Guanyl Yl Cyclase/Natriuretic peptide receptor-A gene disruption causes increased adrenal angiotensin II and aldosterone levels, Am J Physiol Renal Physiology. (Acknowledgement).

Jurgen Lutz, Vanessa Jager, Martin Hempel, Sudesh Srivastav, Maximilian Reiser, Lorenz Jager (2007). Delineation of temporal bone anatomy: feasibility of low-dose 64-row CT in regard to image quality, European Radiology, March 7, 17342488.

Srivastav SK & Shankar A. (2007). On the construction and existence of a certain class of diallel cross designs, Statistics and Probability Letters, volume 77, Issue 1, Pages 111-115.

Diehm N, Kickuth R, Baumgartner I, Srivastav SK, Gretener S, Husmann M, Jaccard Y,  Do DD, Triller J, Bonel HM (2008). MR angiography in infrapopliteal arterial disease: prospective comparison of 1.5 and 3 Tesla magnetic resonance imaging, Investigative Radiology, Volume 42, Number 6, 467-476.

Christos Loupatatzis, Sebastian Schindera, Jan Gralla, Hanno Hoppe, Jan Bittner, Ralph Schröder, Sudesh Srivastav, Harald Marcel Bonel (2008). European Radiology, Whole body computed tomography in multiple trauma using a triphasic injection protocol. European Radiology, volume 18, Number 6, 1206-1214. 

Shaffer JG & Srivastav SK (2009). A Simple Technique for Constructing Optimal Complete Diallel Cross Designs, Statistics and Probability Letters, 79, No. 9, 1181-1185.

Bonel HM, Saar B, Hoppe H, Keo HH, Husmann M, Nikolaou K, Ludwig K, Szucs-Farkas Z, Srivastav SK, Kickuth R (2009).  MR angiography of infrapopliteal arteries in patients with peripheral arterial occlusive disease by using Gadofosveset at 3.0 T: diagnostic accuracy compared with selective DSA. Radiology. 2009 Dec;253(3):879-90.

Nick M. Makridakis1, Troy Phipps, Sudesh Srivastav, and Juergen K.V. Reichardt (2009). PCR-free method detects high frequency of genomic instability in prostate cancer, Nucleic Acids Research, 37(22):7441-7446.

Sandeep Gautam, Jonathan Menachem, Sudesh K. Srivastav, Patrice Delafontaine, and Anand Irimpen (2009). Effect of Hurricane Katrina on the Incidence of Acute Coronary Syndrome at a Primary Angioplasty Center in New Orleans, Disaster Medicine and Public Health Preparedness, August 2009, VOL. 3/NO. 3:1-7.

Steklov, N., Chao, N., Srivastav, S.K. (2010). Patient-Specific Unicompartmental Knee Resurfacing Arthroplasty: Use of a Novel Interference Lock to Reduce Tibial Insert Micromotion and Backside Wear, The Open Biomedical Engineering Journal, vol. 4, 156-161.

Magnus JH,  Doyle MK,  and Srivastav SK (2010). Serum Uric Acid and Self-Reported Rheumatoid Arthritis in a Multiethnic Adult Female, Current Medical Research and Opinion Sep 2010, Vol. 26, No. 9: 2157–2163.

Steklov, Nick, Slamin, John, Srivastav, Sudesh, D'Lima, Darryl (2010). Unicompartmental Knee Resurfacing: Enlarged Tibio-Femoral Contact Area and Reduced Contact Stress Using Novel Patient-Derived Geometries, The Open Biomedical Engineering Journal, vol. 4, 85-92.

Harald Marcel Bonel, Bernhard Stolz, Lars Diedrichsen, Kathrin Frei, Bettina Saar, Boris Tutschek, Luigi Raio,  Daniel Surbek,  Sudesh Srivastav, Mathias Nelle, Johannes Slotboom, and  Roland Wiest (2010). Diffusion-weighted MR Imaging of the Placenta in Fetuses with Placental Insufficiency. Radiology, Volume:  257, 810-819.

Timo Z Nazari-Shafti, Eva Freisinger, Upal Roy, Christine T Bulot, Christiane Senst, Charles L Dupin, Abigail E Chaffin, Debasis Mondal, Eckhard U Alt, Reza Izadpanah and Sudesh K Srivastav (2010). Mesenchymal Stem Cell Derived Hematopoietic Cells are Permissive to HIV-1 Infection, Retrovirology, to appear.

Olugbenga A. Akingbola, Dinesh Singh, Sudesh K. Srivastav, John W. Walsh, David A. Jansen, Edwin M. Frieberg, (2010). Intensive care unit course of infants and children after cranial vault reconstruction for craniosynostosis, Pediatric Critical Care Medicine, to appear.

(Sudesh K Srivastav) Franz Xaver Koeck, Johannes Beckmann, Christian Luring, Bjoern Rath, Joachim Grifka, Erhan Basad (2010). Evaluation of implant position and knee alignment after patient-specific unicompartmental knee arthroplasty, Knee, to appear, Acknowledgement.

Bonel HM, Boller C, Saar B, Tanner S, Srivastav SK, Villiger PM (2010). Short term changes in Magnetic Resonance Imaging and disease activity in response to infliximab, Ann Rheum Dis 69(1):120-125.

Srivastav SK (2010). Characterization of exact random sampling with replacement from finite populations, Submitted.

(Sudesh K Srivastav) Xichun Liu1, Ruijuan Gao1, Yan Dong, Lifang Gao, Yanying Zhao, Lijuan Zhao, Xuejian Zhao, Haitao Zhang (2010). Survivin gene silencing sensitizes prostate cancer cells to selenium growth inhibition, BMC Cancer, 10:418 Acknowledgement.

Jiao Z, Kakoulides S, Moscona J, Whittier J, Srivastav S, Delafontaine P, Irimpen A.  Effect of Hurricane Katrina on incidence of acute myocardial infarction in New Orleans three years after the storm. Am J Cardiol. 2012 Feb 15;109(4):502-5. Epub 2011 Dec 6.

 

Personal Statement:

My research is focused on the study of optimality and constructions of diallel cross design and block designs under different parameters setups (number of treatments or inbred lines, number of blocks, and block size etc). In particular, I am focused on the methodology of arranging experimental units (or subjects e.g. animals, human patients, agricultural units etc.) and the assignment of treatments (different drugs, doses, methods, technique etc.) or inbred crosses in such a way that comparisons among the treatments/lines are as unbiased and as powerful as possible. The aim is to maximize the overall quality of information so that the results and interpretations are optimal and reliable. My work also examines various problems in experimental issues for microarray data, biological sequence alignment, genomic and proteomics analysis, diagnostic and screening analysis, linear models, combinatorial designs, quality controls techniques, and designing and analysis of randomized controlled trials and multi-center clinical trials.

 

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Department of Biostatistics, 1440 Canal Street, Suite 2001, New Orleans, LA 70112, 504-988-5164 kbranley@tulane.edu