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Yao-Zhong Liu, MD PhD
Associate Professor
Department of Biostatistics and Bioinformatics
Tulane University School of Public Health and Tropical Medicine
1440 Canal Street, Suite 2001
New Orleans, LA 70112
Phone: (504) 988-1888
Fax: (504) 988-1706
yliu8@tulane.edu 



Research Interests:

Functional genomics; proteomics; osteoporosis; periodontitis 

 

Memberships:

  • Member, American Society of Human Genetics (ASHG)
  • Member, American Society for Bone and Mineral Research (ASBMR)
  • Member, American Society for Mass Spectrometry (ASMS)
  • Member, International Chinese Hard Tissue Society (ICHTS)

Educational Background:

  • Postdoctoral research, human genetics, University of Texas Health Science Center, Houston, TX, 2006
  • Ph.D., human genetics, Creighton University, Omaha, NE, 2005
  • M.D., Capital University of Medical Sciences, Beijing, P. R. China, 1993

Selected Publications:

Liu YZ, Li J, Pan R, Shen H, Tian Q, Zhou Y, Liu YJ, Deng HW. Genome-wide copy number variation association analyses for age at menarche. J Clin Endocrinol Metab. 2012 Nov;97(11):E2133-9. doi: 10.1210/jc.2012-1145.

Mills KT, Kobori H, Hamm LL, Alper AB, Khan IE, Rahman M, Navar LG, Liu Y, Browne GM, Batuman V, He J, Chen J. Increased urinary excretion of angiotensinogen is associated with risk of chronic kidney disease. Nephrol Dial Transplant. 2012 Aug;27(8):3176-81. doi: 10.1093/ndt/gfs011. Epub 2012 Mar 6.

Deng FY, Dong SS, Xu XH, Liu YJ, Liu YZ, Shen H, Tian Q, Li J, Deng HW. Genome-Wide Association Study Identified UQCC Locus for Spine Bone Size in Humans. Bone. 2012 Nov 30. doi:pii: S8756-3282(12)01390-7. 10.1016/j.bone.2012.11.028.

Yang TL, Guo Y, Shen H, Li J, Glessner JT, Qiu C, Deng FY, Tian Q, Yu P, Liu YZ, Liu YJ, Hakonarson H, Grant SF, Deng HW. Copy Number Variation on Chromosome 10q26.3 for Obesity Identified by a Genome-Wide Study. J Clin Endocrinol Metab. 2012 Nov 21.

Rebholz CM, Wu T, Hamm LL, Arora R, Khan IE, Liu Y, Chen CS, Mills KT, Rogers S, Kleinpeter MA, Simon EE, Chen J. The Association of Plasma Fluorescent Oxidation Products and Chronic Kidney Disease: A Case-Control Study. Am J Nephrol. 2012 Sep 13;36(4):297-304.

Liu YZ, Xu FH, Shen H, Deng HY, Liu YJ, Zhao LJ, V Dvornyk, Conway T, Li JL, Huang QY, Davies KM, Recker RR, Deng HW. 2003. A confirmation linkage study supports that X chromosome harbors a QTL underlying human height variation. J. Med. Genet., 40:825-831.

Liu YZ, Xu FH, Shen H, Liu YJ, Zhao LJ, Long JR, Zhang YY, Xiao P, Xiong DH, Dvornyk V, Li JL, Conway T, Davies KM, Recker RR, Deng HW. 2004. Genetic dissection of human stature in a large sample of multiplex pedigrees. Annals of Human Genetics 68(Pt 5):472-88.    

Liu YZ, Dvornyk V, Lu Y, Shen H, Lappe JM, Recker RR, Deng HW. 2005. A novel pathophysiological mechanism for osteoporosis suggested by an in vivo gene expression study of circulating monocytes. J Biol Chem 280(32):29011-6.

Liu YZ, Guo YF, Xiao P, Xiong DH, Zhao LJ, Shen H, Liu YJ, Dvornyk V, Long JR, Deng HY, Li JL, Deng HW 2006 Epistasis between loci on chromosomes 2 and 6 influences human height. J Clin Endocrinol Metab. 91(10):3821-5.   

Liu YZ, Xiao P, Xiong DH, Zhao LJ, Shen H, Liu YJ, Dvornyk V, Long JR, Deng HY, Li JL, Recker RR, Deng HW 2006 Genetic linkage of human height is confirmed to 9q22 and Xq24. Human Genetics 119(3):295-304.

Dvornyk V, Liu YZ, Lu Y, Shen H, Lappe JM, Lei S, Recker RR, Deng HW. 2007 Effect of menopause on gene expression profiles of circulating monocytes: a pilot in vivo microarray study. J Genet Genomics. 34(11):974-83. 

Visscher PM, Macgregor S, Benyamin B, Zhu G, Gordon S, Medland S, Hill WG, Hottenga J, Willemsen G, Boomsma DI, Liu YZ, Deng HW, Montgomery GW, Martin NG. 2007 Genome Partitioning of Genetic Variation for Height from 11,214 Sibling Pairs. Am J Hum Genet. 81(5):1104-10.

Liu YZ, Wilson SG, Wang L, Liu XG, Guo YF, Li J, Yan H, Deloukas P, Soranzo N, Chinnapen-Horsley U, Cervino A, Williams FM, Xiong DH, Zhang YP, Jin TB, Levy S, Papasian CJ, Drees BM, Hamilton JJ, Recker RR, Spector TD, Deng HW. 2008 Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study. PLoS ONE. 8;3(9):e3160.

Deng FY, Liu YZ, Jiang C, Li LM, Wu S, Chen Y, Jiang H, Yang F, Liu YZ, Xiao P, Xiao SM, Tan LJ, Sun X, Xiong JX, Lei SF, Chen XD, Xiao GG, Xie JY, Liang SP, Deng HW. 2008. Proteomic Analysis of Circulating Monocytes in Chinese Females with Discordant Bone Mineral Density. Proteomics. 8(20):4259-4272

Liu YZ, Pei YF, Guo YF, Wang L, Liu XG, Yan H, Liu JF, Xiong DH, Zhang YP, Jin TB, Levy S, Haddock CK, Papasian CJ, Drees BM, Xu Q, Ma JZ, Payne TJ, Hamilton JJ, Recker RR, Li MD, Deng HW. 2009 Genome-wide association analyses suggested a novel mechanism for smoking behavior regulated by IL15. Molecular Psychiatry 14(7):668-80. 

Liu YZ, Wang L, Tan LJ, Liu XG, Guo YF, Yan H, Xiong DH, Zhang YP, Jin TB, Deng FY, Yu N, Pei YF, Zhang L, Lei SF, Chen XD, Liu HB, Levy S, Papasian CJ, Drees BM, Hamilton JJ, Recker RR, Deng HW. 2009. Genome-wide association analyses identified SPOCK as a key novel gene underlying age at menarche. PLoS Genet. 5(3):e1000420.

Liu YZ, Pei YF, Liu JF, Yang F, Guo Y, Zhang L, Liu XG, Yan H, Wang L, Zhang YP, Levy S, Recker RR, Deng HW. Powerful Bivariate Genome-wide Association Analyses Suggest the SOX6 Gene Influencing Both Obesity and Osteoporosis Phenotypes in Males. 2009 PLoS ONE 28;4(8):e6827. 

Guo Y, Yang TL, Liu YZ, Shen H, Lei SF, Yu N, Chen J, Xu T, Cheng Y, Tian Q, Yu P, Deng HW. 2011.  Mitochondria-Wide Study of Common Variants in Osteoporosis. Ann Hum Genet. July 18 [Epub ahead of print]

Deng FY, Lei SF, Zhang Y, Zhang YL, Zheng YP, Zhang LS, Pan R, Wang L, Tian Q, Shen H, Zhao M, Lundberg YW, Liu YZ, Papasian CJ, Deng HW. 2011. Peripheral blood monocyte-expressed ANXA2 gene is involved in pathogenesis of osteoporosis in humans. Mol Cell Proteomics. 2011 Nov;10(11):M111.011700. Epub 2011 Aug 4.


Level of Instruction:

graduate  

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Department of Biostatistics, 1440 Canal Street, Suite 2001, New Orleans, LA 70112, 504-988-5164 kbranley@tulane.edu