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Yongjun Liu   

Yongjun Liu, MD PhD
Associate Professor
Department of Biostatistics and Bioinformatics
Tulane University School of Public Health and Tropical Medicine
1440 Canal Street, Suite 2033
New Orleans, LA 70112
Phone: (504) 988-1887
Fax: (504) 988-1706
yliu7@tulane.edu 



Research Interests:

Gene identification and functional studies for complex human diseases (such as obesity, osteoporosis, cardiovascular diseases, and sarcopenia) using molecular genetics technologies and statistical genetics methods 

 

Professional Achievements:

 

  • Member, The Scientific Research Society (SICMA XI)
  • Member, The American Society of Human Genetics (ASHG)
  • Member, The American Society for Bone and Mineral Research (ASBMR)
  • Member, North American Association for the Study of Obesity (NAASO)
  • Member, The International Chinese Hard Tissue Society (ICHTS)

Educational Background:

 

  • 2006, Postdoc in Statistical Genetics, University of Alabama, Birmingham, AL
  • 2005, Ph.D. in Biomedical Sciences, Creighton University, Omaha, NE
  • 1993, M.D. in Clinical Medicine, Capital Medical University, Beijing, China

Selected Publications:

Liu YJ, Zhang L, Pei Y, Papasian CJ, Deng HW. On Genome-Wide Association Studies and Their Meta-Analyses: Lessons Learned From Osteoporosis Studies. J Clin Endocrinol Metab. 2013 Jun 19.

Liu YZ, Li J, Pan R, Shen H, Tian Q, Zhou Y, Liu YJ, Deng HW. Genome-wide copy number variation association analyses for age at menarche. J Clin Endocrinol Metab. 2012 Nov;97(11):E2133-9. doi: 10.1210/jc.2012-1145.

Deng FY, Dong SS, Xu XH, Liu YJ, Liu YZ, Shen H, Tian Q, Li J, Deng HW. Genome-Wide Association Study Identified UQCC Locus for Spine Bone Size in Humans. Bone. 2012 Nov 30. doi:pii: S8756-3282(12)01390-7. 10.1016/j.bone.2012.11.028.

Yang TL, Guo Y, Shen H, Li J, Glessner JT, Qiu C, Deng FY, Tian Q, Yu P, Liu YZ, Liu YJ, Hakonarson H, Grant SF, Deng HW. Copy Number Variation on Chromosome 10q26.3 for Obesity Identified by a Genome-Wide Study. J Clin Endocrinol Metab. 2012 Nov 21.

Chen J, Hamm LL, Kleinpeter MA, Husserl F, Khan IE, Chen CS, Liu Y, Mills KT, He C, Rifai N, Simon EE, He J. Elevated plasma levels of endostatin are associated with chronic kidney disease. Am J Nephrol. 2012;35(4):335-40. doi: 10.1159/000336109. Epub 2012 Mar 27.

Deng HW, Deng H, Liu YJ, Liu YZ, Xu FH, Shen H, Conway T, Li JL, Huang QY, Davies KM, Recker RR. A genomewide linkage scan for quantitative-trait loci for obesity phenotypes. Am J Hum Genet 2002; 70: 1138-1151.

Liu YZ, Liu YJ, Recker RR, Deng HW. Molecular studies of gene identification for osteoporosis: The 2002 update. J Endocrinol 2003; 177: 147-196.

Liu YJ, Araujo S, Robert RR, Deng HW. Molecular and Genetic Mechanisms of Obesity: Implications for Future Management. Current Molecular Medicine 2003; 3: 345-360.

Liu YJ, Xu F, Recker RR, Deng HW. Interpretation of genetic linkage findings. J Bone Miner Res 2003; 18:2077-8.

Liu YJ, Xu FH, Shen H, Liu YZ, Deng HY, Zhao LJ, Hong QY, V Dvornyk, Conway T, Davies KM, Li JL, Recker RR, Deng HW. A follow-up study for QTLs contributing to obesity-related phenotypes. J Clin Endocrinol Metab 2004; 89:875-882.

Liu YJ, Rocha SMS, Liu PY, Long J, Deng HW. Tests of linkage and/or association of the LEPR gene polymorphisms with obesity phenotypes in Caucasian nuclear families. Physiol Genomics 2004; 17:101-6.

Dvornyk V., Shen H, Liu YJ, Xiao P, Recker RR, Deng HW. Systematic approaches to the study of complex bone disorders at whole-genome level. Current Genomics 2004; 5:93-108.

Shen H, Liu YJ, Liu PY, Recker RR, and Deng HW. Nonreplication in Genetic Studies of Complex Diseases - Lessons Learned from Studies of Osteoporosis. J Bone Miner Res 2005; 20 (3):365-376.

Liu YJ, Shen H, Xiong DH, Xiao Peng, Li Lihua, Recker R, Deng HW. Molecular Genetic Studies of Gene Identification for Osteoporosis: a 2004 update. J Bone Miner Res 2006 Oct;21(10):1511-35.

Zhao LJ, Liu YJ, Liu PY, Hamilton J, Recker RR, Deng HW.  Relationship of obesity with osteoporosis. J Clin Endocrinol Metab. 2007 May;92(5):1640-6.

Liu YJ, Liu XG, Wang L, Dina C, Yan H, Liu JF, Levy S, Papasian CJ, Drees BM, Hamilton JJ, Meyre D, Delplanque J, Pei YF, Zhang L, Recker RR, Froguel P, Deng HW.  Genome-wide association scans identified CTNNBL1 as a novel gene for obesity. Hum Mol Genet. 2008 Jun 15;17(12):1803-13.

Liu YJ, Papasian CJ, Liu JF, Hamilton J, Deng HW. Is replication the gold standard for validating genome-wide association findings? PLoS ONE. 2008;3(12):e4037.

Liu Y, Ordovas JM, Gao G, Province M, Straka RJ, Tsai MY, Lai CQ, Zhang K, Borecki I, Hixson JE, Allison DB, Arnett DK. Pharmacogenetic association of the APOA1/C3/A4/A5 gene cluster and lipid responses to fenofibrate: the genetics of lipid-lowering drugs and diet network study. Pharmacogenet Genomics. 2009 Feb;19(2):161-9.

DE Moor MH*, Liu YJ*, Boomsma DI, Li J, Hamilton JJ, Hottenga JJ, Levy S, Liu XG, Pei YF, Posthuma D, Recker RR, Sullivan PF, Wang L, Willemsen G, Yan H, DE Geus EJ, Deng HW. Genome-Wide Association Study of Exercise Behavior in Dutch and American Adults. Med Sci Sports Exerc. 2009 Sep 2. [Epub ahead of print] (*co-first author).

Liu YJ, Guo YF, Zhang LS, Liu XG, Papasian CJ, Deng HW. Biological Pathway-Based Genome-Wide Association Analysis Identified the VIP Pathway Important for Obesity. Obesity (Silver Spring). (in press). 

 

Level of Instruction:

graduate  

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Department of Biostatistics, 1440 Canal Street, Suite 2001, New Orleans, LA 70112, 504-988-5164 kbranley@tulane.edu