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Novel Compounds Effective Against Tumor Growth (PDF)

Tulane University is actively seeking companies interested in commercializing novel compounds
which are effective antagonists of ghrelin, growth hormone releasing peptide and the growth
hormone secretagogue receptor.

 

Applications

Provides effective treatment of hormonally functional endocrine or non-endocrine tumors,
including breast, prostate, pituitary, functional ectopic neuroendocrine, carcinoid, pancreatic and
others

 

Advantages

These peptide compounds are relatively short (less than 10 amino acids) and act at the level of
the central nervous system. Peptides are generally easy to manufacture and purify and tend to
have very low toxicity profiles.

 

Technology

This technology has been tested extensively in vitro and in vivo in a rat model, with results
strongly supporting the efficacy of the compounds. Laboratory work is ongoing to produce more
effective species of these compounds.

 

Inventors

Cyril Bowers, Ph.D., David Coy, Ph.D., Simon Hocart, Ph.D., Gloria Tannenbaum, Ph.D.

 

For more information, please contact:

John Christie
Executive Director
504-988-6962
jchrist@tulane.edu

Tulane University, New Orleans, LA 70118 504-865-5000 website@tulane.edu