Federal Regulations

  • A-110 - Uniform Administrative Requirements for Grants and Agreements With Institutions of Higher Education, Hospitals and Other Non-Profit Organization

    A-110 establishes uniform administrative requirements for federal awards to institutions of higher education. It defines pre and post award requirements, property management standards, procurement standards, and reporting and record retention.

  • A-21 - Principles for Determining Costs Applicable to Grants, Contracts and Other Agreements With Educational Institutions

    A-21 provides principles for determining the costs applicable to research, development, training, and other sponsored work performed by colleges and universities under grants, contracts or other agreements with the federal government. These cost accounting principles are a guide in determining allowable costs. The circular includes a definition of terms, what constitutes direct and indirect costs, and general provisions for selected items of cost.

  • A-133 - Audits of Institutions of Higher Education and Other Non-Profit Institutions

    This circular sets standards for obtaining consistency and uniformity among federal agencies for the audit of non-profit organizations expending federal funds. It defines audit requirements, auditee responsibilities, responsibilities of the federal agencies, and delineates the scope of what can be audited.

  • 45CFR46 - Protection of Human Subjects

    This section of the Code of Federal Regulation provides safeguards and protection of human subjects used in research. This policy applies to all research involving human subjects conducted, supported or otherwise subject to regulation of any federal department or agency. Other than certain exempt categories, research involving human subjects is subject to review by an institutional committee operating in accordance with the requirements of the policy.

  • Public Health Service Policy on Humane Care and Use of Laboratory Animals

    The Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals sets forth the requirements that are applicable to all research, research training, biological testing, and related activities involving animals that are supported or conducted by agencies of the PHS. The Office for Protection from Research Risks (OPRR) at the National Institutes of Health is responsible for the general administration and coordination of the Policy.

  • National Science Foundation (NSF) Grant Policy Manual

    This Grant Policy Manual (GPM) is a compendium of basic NSF  policies and procedures for use by the grantee community and NSF staff. Its coverage includes the NSF award process, from  issuance and administration of an award through closeout. Guidance regarding other grant requirements or considerations which either are not universally applicable or which do not follow the award cycle is also provided. 

  • NIH Guide - PHS Grants Policy Statement

    This publication presents a compilation of the salient features of policies and various policy issues that have been raised in the past regarding the administration of Public Health Service (PHS) grant awards. 


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